TRAINING PROGRAM IN BIOMEDICAL IMAGING AND INFORMATIONAL SCIENCES

首席研究员/项目主任（最后，第一，中间）：吉，詹姆斯C。 项目摘要 临床相关成像科学的定量基础科学家的培训越来越重要。 优秀的成像科学在宾夕法尼亚大学的多个学校都有很好的代表性，但以前没有正式的 研究生培训中的整合工作存在，也没有正式的临床培训部分，直到 创建生物医学成像和信息科学培训计划。成立于2006年 在HHMI-NIBIB接口倡议的支持下，该计划目前代表着一种由以下各方领导的伙伴关系： 放射学，生物工程，计算机和信息科学系，与 许多其他部门在多个学校。我们的前提是，最成功的研究和 定量成像科学中的技术是那些整合了临床相关性，数学严谨性， 工程技术因此，该计划包括强大的临床曝光以及分析成像 科学目标是提供跨学科培训，确保学生达到 整合，使他们成为下一代领导者，在假设驱动，临床为重点， 生物医学成像研究。迄今为止，所有影响措施的方案成果都很强劲，表明 朝着培训目标取得成功进展：出版物（219）和引文（5171）;大量研究 获奖和荣誉;招聘9名（23%）URM或弱势学员;和14名毕业生（78%）在 教师职位，博士后培训，或医疗培训和住院医师。 一个正式的课程，博士基金会，为该计划提供了18个月的垂直 生物医学核心教学要素与生物医学成像基础科学教育的整合 通过三个基础组成部分，其次是选修途径。首先，生物医学基础 科学（2门课程），学生参加医学生课程的模块1和2，教授 医学核心原理（包括大体解剖学）和12个月的器官系统序列 医学、综合系统和疾病。这是由成像基础2门课程的补充 科学：分子成像和成像的基本技术。第三个基本组成部分是 专业培训：负责任的研究行为，科学严谨性和再现性，教学 实习，以病人为导向的研究培训，研究'生存'技能，和职业发展技能。的 基础课程通过许多选修课程向更专业的培训延伸， 两条途径-成像方法和应用以及成像数据科学-后者是下一个新途径 更新期。教学培训由强制性的实验室轮换补充，通过 参与教师的实验室。确保论文研究方向是转化医学 通过解决离散的临床问题，学员需要得到委员会成员的共同建议 临床和基础科学系。 PHS 398（Rev. 11/07）

Principal Investigator/Program Director (Last, First, Middle): Gee, James C. Project Summary The training of quantitative basic scientists in clinically-related imaging science is increasingly important. Excellent imaging sciences are well represented at Penn in multiple schools, but previously no formal integration of efforts in graduate training existed, nor was there a formal clinical component to the training until the creation of the Training Program in Biomedical Imaging and Informational Sciences. Established in 2006 under the auspices of the HHMI-NIBIB Interfaces Initiative, today the program represents a partnership led by the Departments of Radiology, Bioengineering, and Computer and Information Science, in collaboration with many other Departments across multiple Schools. Our premise is that the most successful research and technologies in quantitative imaging science are those that integrate clinical relevance, mathematical rigor, and engineering finesse. Accordingly, the program embraces strong clinical exposure alongside analytical imaging science. The objective is to provide interdisciplinary training by ensuring that students attain a level of integration that will allow them to become the next generation of leaders in hypothesis-driven, clinically-focused biomedical imaging research. Program outcomes to date are strong across all impact measures, indicating successful progress toward training objectives: publications (219) and citations (5171); numerous research awards and distinctions; recruitment of 9 (23%) URM or disadvantaged trainees; and 14 graduates (78%) in faculty positions, post-doctoral training, or medical training and residencies. A formalized curriculum, the doctoral foundation, developed for the program provides 18 months of vertical integration of the core didactic elements of biomedicine and basic science education in biomedical imaging through three Foundational components, followed by elective Pathways. In the first, Foundations in Biomedical Science (2 courses), students participate in modules 1 and 2 of the medical student curriculum that teaches the Core Principles of Medicine (including Gross Anatomy) and a 12-month sequence of organ systems medicine, Integrative Systems and Diseases. This is complemented by 2 courses in Foundations of Imaging Science: Molecular Imaging, and Fundamental Techniques of Imaging. The third foundational component is Professional Training: Responsible Conduct of Research, Scientific Rigor and Reproducibility, Teaching Practicum, Patient-Oriented Research Training, Research `Survival' Skills, and Career Development Skills. The foundational curriculum is extended toward more specialized training by many elective courses offered through two Pathways – Imaging Methods and Applications, and Imaging Data Science – the latter new in the next renewal period. Didactic training is complemented by obligatory Laboratory Rotations that are offered through the laboratories of participating faculty. To ensure that the thesis research is directed to translational medicine through the solution of discrete clinical problems, trainees are required to be co-advised by members of the clinical and basic science faculty. PHS 398 (Rev. 11/07) Page Continuation Format Page