Threat-Related Negative Valence Systems, Child Victimization, and Anxiety_Supplement

与威胁相关的负价系统、儿童受害和焦虑_补充

• 批准号: 10597417
• 负责人: CARLA KMETT DANIELSON
• 金额: $ 22.11万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-01 至 2024-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10597417
• 关键词: Accounting; Acute; Address; Administrative Supplement; Adolescence; Affect; Age; Amygdaloid structure; Anterior; Anxiety; Behavioral; Biological; COVID-19 pandemic; Childhood; Classification; Clinical assessments; Collection; Communities; Data Collection; Development; Diagnosis; Ensure; Event-Related Potentials; Exposure to; Funding; Goals; Guidelines; Hydrocortisone; Insula of Reil; Interpersonal Violence; Intervention; Lead; Link; Longevity; Longitudinal Studies; Longitudinal cohort; Measures; Mediating; Mental Health; Mental disorders; Negative Valence; Outcome; Panic; Participant; Pattern; Persons; Phenotype; Physiological; Physiology; Plant Roots; Prevention; Psychopathology; Research; Research Domain Criteria; Risk; Risk Factors; Sampling; Societies; Startle Reaction; Symptoms; System; Telephone; Testing; Time; TimeLine; Translating; Visit; Writing; Youth; anxiety states; anxiety symptoms; anxious; associated symptom; base; boys; child and adolescent victimization; cingulate cortex; cohort; cost; data cleaning; design; emotional distress; experience; follow-up; functional MRI scan; girls; improved; magnetic resonance imaging/electroencephalography; neuroimaging; pandemic disease; parent project; participant retention; personalized medicine; physical conditioning; predicting response; psychologic; recruit; relating to nervous system; resilience; response; self-reported anxiety; sex; violence exposure

Interpersonal violence (IPV) exposure affects 1 in 2 youth and levies tremendous physical and mental health burdens on victims and society. Childhood IPV exposure is a well-established risk factor for anxiety and other mental health problems across the lifespan. A paucity of longitudinal studies assessing multiple threat-related mechanisms, across multiple units of analysis, and at key times in development has been a critical barrier to informing the design of personalized treatments to target root causes of post-IPV psychopathology. The overarching goal of this project (the “CHARM study”) is to examine developmental trajectories of threat-related NVS measures into adolescence, as a function of exposure to IPV, in an effort to better link IPV and anxiety through changes in these measures. The specific aims of this project are: 1) to identify threat-related NVS constructs that connect lifetime IPV to anxious symptoms in youth cross-sectionally; 2) to investigate longitudinally the degree to which IPV sensitizes trajectories of NVS measures across three age cohorts (grades 3, 6, 9 at baseline); and 3) to investigate the degree to which trajectories of NVS measures predict anxiety symptoms over time after accounting for initial anxiety symptoms and IPV status. The study had successfully recruited its full sample (N=364) and longitudinal retention was progressing as planned until March, 2020, when the COVID-19 pandemic (and subsequent mandatory guidelines impacting in-person data collection) reduced retention across the representative sample. Pandemic disruptions have required increased intensive efforts in participant retention, particularly for the final assessment (Lab Visit 3) that includes the follow-up fMRI scan, which has translated into a delayed timeline and increased costs. The proposed Administrative Supplement is essential to help cover these unexpected costs to complete the outstanding in-person data collection, as well as final data cleaning, analysis, and write up of results, ensuring that the longitudinal aims are successfully met and that maximum impact is yielded from the study.

每两个青少年中就有一人受到人际暴力（IPV）的影响，并对身心健康造成巨大影响

项目成果

A qualitative analysis of black mother preparation for bias messages following incidents of racism-related violence.

对黑人母亲在种族主义相关暴力事件后对偏见信息的准备情况进行定性分析。

• DOI: 10.1037/fam0001162
• 发表时间: 2024
• 期刊: Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43)
• 作者: Bernard,DonteL;Saleem,FarzanaT;Moreland,AngelaD;Shacklewood,Curtisha;Danielson,CarlaKmett
• 通讯作者: Danielson,CarlaKmett

Risk reduction through family therapy (RRFT): Protocol of a randomized controlled efficacy trial of an integrative treatment for co-occurring substance use problems and posttraumatic stress disorder symptoms in adolescents who have experienced interperson

通过家庭治疗（RRFT）降低风险：针对经历过人际交往的青少年同时发生的物质使用问题和创伤后应激障碍症状进行综合治疗的随机对照疗效试验方案

• DOI: 10.1016/j.cct.2020.106012
• 发表时间: 2020
• 期刊: Contemporary clinical trials
• 影响因子: 2.2
• 作者: Hahn,AustinM;Adams,ZacharyW;Chapman,Jason;McCart,MichaelR;Sheidow,AshliJ;deArellano,MichaelA;Danielson,CarlaKmett
• 通讯作者: Danielson,CarlaKmett