Mentorship and Research in HIV and Addiction Prevention Among Traumatized Youth

此次K24续约的目的是继续以指数方式增强Carla Kmett Danielson博士的指导 研究项目，以创新的方法减少艾滋病毒感染和成瘾的风险， 青少年，特别关注创伤暴露人群。在K24融资期间，博士。 临床心理学家和科学家丹尼尔森证明，她是这种机制的理想人选。的 她在扩大研究和指导方面受到保护的时间的影响通过许多成就显而易见 包括23名学员的生产性指导（来自代表性不足的学员的比例>50%） 背景），表彰这种指导的奖项，在mHealth艾滋病毒和成瘾的新的研究线 预防干预，并继续联邦资助她的创新病人为导向的研究（POR）， 她让她的学员参与进来。她的学员包括早期职业教师、博士后研究员， 和博士前心理学实习生，正在为艾滋病毒预防，药物滥用， 和创伤应激领域通过高影响力的出版物和新的线NIH资助的研究。的 建议的K24奖励更新对于为候选人提供必要的时间和资源至关重要 扩大她在虚拟现实技术方面的研究技能，为艾滋病毒感染高风险的年轻人提供服务， 成瘾，维持她的指导计划和能力，并进一步刺激她的研究计划， 学员（例如，通过在前一个资助期内成功的受训飞行员奖励计划）。 Danielson博士在K24更新下提出的创新研究涉及对一种 虚拟现实临床工具，以改善创伤知情评估和预防物质使用和性行为 危险行为的风险。这将通过主要专家的投入和培训来实现 在虚拟现实-高风险行为研究领域;国际知名的虚拟现实技术公司 工具开发（Virtually Better，Inc.）;定性研究;消费者和专家咨询委员会;以及 对高风险人群的有效性、可接受性和可行性进行评估 (e.g.,接受药物使用问题和创伤性压力治疗的青少年; 高风险艾滋病毒诊所）和卫生保健提供者。丹尼尔森博士提议的指导活动，目前联邦政府- 资助的研究项目，并旨在追求创新，虚拟现实研究领域的艾滋病毒预防， 药物使用风险减少和青少年创伤与NIDA优先事项协调一致， 旨在评估新技术应用情况的研究，以提供适应性预防 针对药物使用和预防艾滋病毒感染的干预措施。这项研究为丰富 为她的学员提供培训机会（重点是来自临床代表性不足的群体的学员） 科学），并将为艾滋病毒感染和成瘾风险的年轻人提供新的POR方向。

The purpose of this K24 renewal is to continue to exponentially enhance Dr. Carla Kmett Danielson's mentorship and research program in innovative approaches to risk reduction of HIV acquisition and addiction among adolescents, with a particular focus on trauma-exposed populations. Over the prior K24 funding period, Dr. Danielson, a clinical psychologist and scientist, demonstrated she is the ideal candidate for this mechanism. The impact of her protected time for expanded research and mentorship are evident through numerous achievements from over this funding period, including productive mentorship of 23 mentees (>50% from underrepresented backgrounds), awards in recognition of this mentorship, a new line of research in mHealth HIV and addiction prevention intervention, and continuous federal-funding of her innovative patient oriented research (POR) in which she has involved her mentees. Her mentees, who have included early-career faculty, post-doctoral fellows, and predoctoral psychology interns, are making significant contributions to the HIV prevention, substance abuse, and traumatic stress fields through high-impact publications and new lines of NIH-funded research. The proposed K24 award renewal will be essential for providing the time and resources necessary for the candidate to expand her research skills in virtual reality technologies for young people at high risk for HIV acquisition and addiction, sustain her mentoring program and capacity, and further stimulate the research program of her mentees (e.g., through a trainee pilot award program that was successful during the prior funding period). Innovative research proposed by Dr. Danielson under the K24 renewal involves refinement and evaluation of a virtual reality clinical tool to improve trauma-informed assessment and prevention of substance use and sexual risk behavior with at-risk young people. This will be accomplished through input and training from leading experts in the virtual reality-high risk behavior research field; an internationally known technology firm in virtual reality tool development (Virtually Better, Inc.); qualitative research; an Advisory Board of consumers and experts; and evaluation of the validity, acceptability, and feasibility of the refined virtual reality tool with high risk populations (e.g., adolescents in treatment for substance use problems and traumatic stress; young adults presenting to a high-risk HIV clinic) and health care providers. Dr. Danielson's proposed mentorship activities, current federally- funded research projects, and aims to pursue innovative, virtual reality research in the areas of HIV prevention, substance use risk reduction, and trauma among adolescents harmonize well with NIDA priorities that call for research designed to evaluate the application of new technologies for delivering adapted prevention interventions targeting substance use and prevention of HIV acquisition. The proposed research affords rich training opportunities for her mentees (with an emphasis on trainees from groups under-represented in clinical science) and will invigorate new directions in POR with young people at risk for HIV acquisition and addiction.