Career Development in Pediatric and Medical Oncology

儿科和肿瘤内科的职业发展

• 批准号: 10601328
• 负责人: NANCY ELLEN DAVIDSON
• 金额: $ 68.14万
• 依托单位: FRED HUTCHINSON CANCER CENTER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-30 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10601328
• 关键词: Career; Development; Pediatric; Medical; Oncology

PROJECT SUMMARY/ABSTRACT We are requesting funds for The Paul Calabresi Career Development Award for Clinical Oncology in Pediatric and Medical Hematology/Oncology at the Fred Hutchinson Cancer Research Center, University of Washington School of Medicine and Seattle Children’s Hospital. The Career Development Program will interface with our Pediatric Hematology/Oncology, Medical Oncology, and adult Hematology Training Programs at the Fred Hutchinson Cancer Research Center and the Departments of Pediatrics and Medicine at the University of Washington, with the goal of developing and supporting transition of clinical translational investigators into independent investigators. This K12 Career Development Award for Clinical Oncology will be an integral part of our program towards grooming the next generation of independent clinical researchers by supporting four physicians each year who have completed fellowship training in the pediatric or medical hematology/oncology training programs with track record of promising independent clinical/translational careers. Prior to entry into the program, scholar candidates will have acquired clinical skills and basic laboratory tools of modern biology and translation of laboratory findings to clinical application. Those most qualified and motivated to enter into investigative endeavors in clinical translational research will be selected. The K12 scholars will receive two to three years of funding to help develop requisite experience to conduct clinical translational research, translate their findings to patients, and generate sufficient data to help establish independent research careers. The aim of their projects will be to contribute new and useful information relevant to clinical oncology and to develop the clinical research capabilities of the trainees. The supported research projects include those in the areas of hematopoietic stem cell transplantation, immunology and immunotherapy, transplantation biology, outcome and quality of life research, malignant hematopoiesis, human immunogenetics, and programs in solid tumor research including tumors of the brain, breast, ovaries, prostate, and breast. Additional projects in molecular biology and gene therapy, as well as other relevant research arenas, will be available. Trainees will also gain experience in clinical protocol development, conduct, and evaluation, and will receive didactic training in biostatistics, clinical trial design and biomedical research integrity. This program utilizes the laboratory and clinical research facilities of the Fred Hutchinson Cancer Research Center, the University of Washington, and the Seattle Children’s Hospital Research Institute, and the clinical facilities of the Seattle Cancer Care Alliance, The University of Washington, and the Seattle Children’s Hospital.

项目摘要/摘要 我们正在为保罗·卡拉布雷西儿科临床肿瘤学职业发展奖申请资金 华盛顿大学弗雷德·哈钦森癌症研究中心的医学血液学/肿瘤学 医学院和西雅图儿童医院。职业发展计划将与我们的 弗雷德医院的儿童血液学/肿瘤学、内科肿瘤学和成人血液学培训计划 哈钦森癌症研究中心和加州大学儿科和医学系 华盛顿，目标是发展和支持临床翻译研究人员过渡到 独立调查人员。K12临床肿瘤学职业发展奖将是不可或缺的一部分 我们的计划旨在通过支持四个项目培养下一代独立的临床研究人员 每年完成儿科或内科血液学/肿瘤学团契培训的医生 具有良好的独立临床/翻译职业记录的培训计划。在进入之前 在该计划中，奖学金获得者将获得现代生物学的临床技能和基本实验室工具 以及将实验室结果转化为临床应用。那些最有资格和最有动力进入的人 临床转化性研究中的研究努力将被选中。 K12奖学金获得者将获得两到三年的资助，以帮助发展必要的经验来进行 临床转化性研究，将他们的发现翻译给患者，并生成足够的数据来帮助建立 独立研究职业。他们项目的目的将是提供新的有用的信息 与临床肿瘤学相关，并培养学员的临床研究能力。受支持的 研究项目包括造血干细胞移植、免疫学和 免疫治疗，移植生物学，结果和生活质量研究，恶性造血，人类 免疫遗传学和实体肿瘤研究项目，包括脑、乳腺、卵巢、前列腺、 还有乳房。在分子生物学和基因治疗以及其他相关研究方面的其他项目 竞技场，将是可用的。受训人员还将获得临床方案开发、实施和 评估，并将接受生物统计学、临床试验设计和生物医学研究方面的教学培训 正直。 该计划利用弗雷德·哈钦森癌症研究中心的实验室和临床研究设施 华盛顿大学和西雅图儿童医院研究所，以及临床 西雅图癌症护理联盟、华盛顿大学和西雅图儿童基金会的设施 医院。