Problem-to-Product Team Entrepreneurship and Active Mentoring (P2P-TEAM) Graduate Training Program

问题到产品团队创业与主动指导（P2P-TEAM）研究生培训计划

• 批准号: 10620850
• 负责人: Jennifer S. Brodbelt
• 金额: $ 17.44万
• 依托单位: UNIVERSITY OF TEXAS AT AUSTIN
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10620850
• 关键词: Entrepreneurship; Mentors; Training Programs

Project Summary Our proposed predoctoral training program “Problem-to-Product Team Entrepreneurship and Active Mentoring” (P2P-TEAM) embraces a team science approach to research training, with an emphasis on entrepreneurial skills and professional development. The program will train the next generation of students to flourish in scientifically diverse teams and embrace an entrepreneurial perspective that will benefit the many graduate students in STEM fields who transition into industrial careers, as well as those pursuing academic or government career paths. The program revolves around the formation of interdisciplinary teams, which serve as the nuclei for pursuing advanced research projects related to the overarching theme of theranostics, a new approach to personalized medicine combining targeted therapy and diagnosis. The program will engage students in team-based collaborative projects and encourage entrepreneurial efforts that build directly from translational impact (i.e., prospects for technology transfer and commercialization). The team-based collaboration model is designed to increase accountability, develop peer networks and support systems, and motivate students to see their individual research efforts in the context of solving bigger problems with potentially translational payoffs, while the emphasis on entrepreneurship is designed to foster innovation and develop an understanding of the business world and industry practices. The program is planned for two trainees in the first year, then a steady-state of five trainees in subsequent years. The duration of each appointment is 2 years. Key programmatic features of the P2P-TEAM program include (i) collaborative research, (ii) entrepreneurial training, and (iii) professional development. The training program has 5 overarching goals: (1) facilitate the development of interdisciplinary peer teams, (2) improve scientific communication, (3) encourage an entrepreneurial perspective and business acumen not typically fostered in traditional graduate programs, (4) develop project management skills, and (5) enhance professional training (soft skills). Specific activities include training in translation of research problems into products; participation in professional development, statistical informatics, and entrepreneurship courses; activities to build networking and scientific communication skills; creation of an annual prospectus; and engagement in industrial internships. Industrial mentors will provide insight into the business aspects related to assessment of technology development arising from the collaborative research projects. The frontier field of theranostics provides avenues for both basic and applied research projects, as well as natural translation to commercialization opportunities, making it an ideal focus of the proposed training program. Because of its interdisciplinary and translational research approach, our program will be an avenue for recruiting and retaining highly innovative graduate students from diverse backgrounds.

项目摘要 我们建议的博士前培训计划“问题到产品团队创业和积极的指导” （P2P-TEAM）采用团队科学方法进行研究培训，重点是创业技能 和职业发展。该计划将培养下一代学生在科学上蓬勃发展 多元化的团队，并拥抱创业的角度，这将有利于许多研究生在干 谁过渡到工业职业领域，以及那些追求学术或政府职业道路。的 该计划围绕跨学科团队的形成，作为追求的核心 与治疗诊断学的总体主题相关的高级研究项目，个性化治疗的新方法 结合靶向治疗和诊断的药物。该计划将使学生参与以团队为基础的 合作项目，并鼓励直接从转化影响中建立的创业努力（即， 技术转让和商业化的前景）。基于团队的协作模式旨在 加强问责制，发展同伴网络和支持系统，并激励学生看到他们的 在解决具有潜在转化回报的更大问题的背景下的个人研究努力，而 强调企业家精神是为了促进创新和发展对企业的理解 世界和行业惯例。该计划计划在第一年为两名学员，然后稳定为五名 在随后的几年里，每次任命的期限为2年。 P2P-TEAM计划的主要方案特征包括（一）合作研究，（二）创业 （三）职业发展。培训计划有5个总体目标：（1）促进 发展跨学科同行团队，（2）改善科学交流，（3）鼓励 传统研究生课程通常不会培养企业家的视角和商业头脑，（4） 培养项目管理技能;（5）加强专业培训（软技能）。具体活动包括 将研究问题转化为产品的培训;参与专业发展、统计 信息学和创业课程;建立网络和科学交流技能的活动; 编制年度计划书;参与工业实习。工业导师将提供见解 技术开发评估所涉及的业务方面， 研究项目。治疗诊断学的前沿领域为基础和应用研究提供了途径 项目，以及自然转化为商业化的机会，使其成为一个理想的重点， 提出的培训计划。由于其跨学科和翻译研究方法，我们的计划将 成为招聘和留住来自不同背景的高度创新的研究生的途径。

项目成果

Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein.

• DOI: 10.1016/j.chom.2022.07.016
• 发表时间: 2022-09-14
• 期刊: CELL HOST & MICROBE
• 影响因子: 30.3
• 作者: Javanmardi, Kamyab;Segall-Shapiro, Thomas H.;Chou, Chia-Wei;Boutz, Daniel R.;Olsen, Randall J.;Xie, Xuping;Xia, Hongjie;Shi, Pei-Yong;Johnson, Charlie D.;Annapareddy, Ankur;Weaver, Scott;Musser, James M.;Ellington, Andrew D.;Finkelstein, Ilya J.;Gollihar, Jimmy D.
• 通讯作者: Gollihar, Jimmy D.

Proximity-Driven DNA Nanosensors.

• DOI: 10.1149/2754-2726/ace068
• 发表时间: 2023-09-01
• 期刊: ECS sensors plus