Administrative Core

行政核心

• 批准号: 10628879
• 负责人: W KEITH MISKIMINS
• 金额: $ 20.49万
• 依托单位: SANFORD RESEARCH/USD
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2028-02-29
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10628879
• 关键词: Address; Advisory Committees; Agreement; Annual Reports; Applications Grants; Area; Budgets; Cancer Biology; Cancer Center; Collaborations; Committee Members; Consultations; Country; Data; Decision Making; Development; Disputes; Eligibility Determination; Ensure; Faculty; Fee-for-Service Plans; Feedback; Fees; Flow Cytometry; Fostering; Funding; Goals; Grant; Histology; Image; Immune response; Institution; Joints; Lead; Leadership; Malignant Neoplasms; Manuscripts; Mentors; Mission; North Dakota; Phase; Pilot Projects; Principal Investigator; Productivity; Program Reviews; Progress Reports; Publications; Report (document); Reporting; Research; Research Activity; Research Personnel; Resolution; Role; Scientific Evaluation; Services; Site; Specialist; Structure; System; United States National Institutes of Health; Universities; Work; Writing; anticancer research; base; cohesion; falls; individual responsibility; innovation; meetings; member; nerve supply; operation; programs; research faculty; success; tumor; tumor microenvironment; virtual; voucher; waiver

Abstract The Administrative Core (Core A) of the Center for Cancer Biology Research (CCBR) at Sanford Research is not only essential for all research activities occurring within the CCBR but also for that within Sanford Research as a whole. The funds requested in Phase III will provide continued support for the Principal Investigator, Program Coordinator and Project Manager. These key individuals are responsible for the overall administration of the CCBR. We also propose to fully support the Lead Research Technician and Senior Research Specialist of the Histology & Imaging Core (Core B) as well as a Manager and Technician in the Flow Cytometry Core (Core C). We will additionally support a Pilot Grant program to ensure continued funding of innovative research in the region and use of the CCBR's Scientific Cores. A Steering Committee composed of previous CoBRE Project Leaders as well as Sanford Research leaders will ensure successful functioning of the Scientific Cores. An External Advisory Committee, composed of leaders in the Cancer Biology field, will work with external reviewers from North Dakota State University, the Administrative Core and the Steering Committee to select Pilot Grant awardees and resolve any issues that may arise within the CCBR or its Scientific Cores. The Administrative Core will accomplish the following Specific Aims: 1) To support the existing Scientific Cores, enabling self-sufficiency and 2) To continue a program of Pilot Grants. In order to achieve these goals, the Administrative Core will meet twice a year (Fall and Spring) with the Steering and External Advisory Committees. The Spring meeting will serve as a review of the program and evaluation of the Scientific Cores as they work towards self-sustainability. Importantly, the Administrative Core will prioritize and oversee the allocation of funds such that they meet institutional strategic needs and are in line with the NIH mission. Moreover, the Administrative Core will continue to focus on the CCBR's existing areas of cancer research while expanding to include additional innovative and impactful areas. The CCBR will have the following focus areas: 1) tumor innervation, 2) tumor immune response, 3) tumor microenvironment and 4) tumor development. The ultimate goals of the Administrative Core are to continue funding cancer research in the region and to bring the CCBR's Scientific Cores to self-sufficiency. The plan laid out in this section will ensure success of the CCBR.

摘要 桑福德研究所癌症生物学研究中心(CCBR)的行政核心(核心A)是 不仅对CCBR内发生的所有研究活动至关重要，而且对Sanford Research内的研究活动也是如此 作为一个整体。第三阶段请拨的资金将继续为首席调查员提供支助， 项目协调员和项目经理。这些关键人员负责整个行政管理 CCBR的。我们还建议全力支持首席研究技术员和高级研究专家 组织与成像核心(核心B)以及流式细胞仪核心的经理和技术人员 (核心C)。我们还将支持一项试点助学金计划，以确保继续为创新研究提供资金 以及CCBR科学核心的使用情况。由前任科布雷组成的指导委员会 项目负责人以及桑福德研究项目负责人将确保科学核心的成功运作。 一个由癌症生物学领域的领导人组成的外部咨询委员会将与外部 来自北达科他州立大学、行政核心和指导委员会的评审员选择 试点获奖者奖励并解决CCBR或其科学核心内可能出现的任何问题。这个 管理核心将实现以下具体目标：1)支持现有的科学核心， 实现自给自足；2)继续试点赠款计划。为了实现这些目标， 行政核心每年将与指导委员会和外部咨询委员会举行两次会议(秋季和春季)。 春季会议将作为对科学核心工作的方案和评估的审查 走向自我维持。重要的是，行政核心将确定资金分配的优先次序并对其进行监督 以满足机构的战略需求，并与国家卫生研究院的使命保持一致。此外， 管理核心将继续专注于CCBR现有的癌症研究领域，同时扩大到 包括更多创新和有影响力的领域。CCBR将有以下重点区域：1)肿瘤 神经支配；2)肿瘤免疫反应；3)肿瘤微环境；4)肿瘤发展。终极的 行政核心的目标是继续资助该地区的癌症研究，并将CCBR的 科学核心转向自给自足。本节列出的计划将确保CCBR的成功。