Administrative Core

行政核心

• 批准号: 10900839
• 负责人: Robert J. Coffey
• 金额: $ 104.07万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10900839
• 关键词: Agreement; Atlases; Cells; Collaborations; Colorectal; Communication; Data; Data Analyses; Development; Dictionary; Ensure; Environment; Evaluation; Expenditure; Feedback; Fostering; Funding; Infrastructure; Institution; Interdisciplinary Study; Lead; Leadership; Metadata; Neoplastic Cell Transformation; Policies; Procedures; Process; Regulation; Reporting; Research; Resource Sharing; Sampling; Secure; Shapes; System; United States National Institutes of Health; Vision; Work; adenoma; data exchange; data sharing; experience; improved; member; multidisciplinary; operation; organizational structure; premalignant; programs; recruit; success; tool

Project Summary: Administrative Core The leadership of the Vanderbilt Pre-Cancer Atlas (PCA) Center builds on an existing multidisciplinary team that has been working together for over 15 years on the Vanderbilt GI Special Programs of Research Excellence (SPORE). We have also recruited additional team members from Johns Hopkins to round out expertise for the atlas construction. Each team member also has extensive experience in collaborative research efforts across multiple studies and multiple institutions. The Administrative Core will provide the primary scientific oversight for the Vanderbilt PCA activities. It will have primary management and oversight responsibility for all Pre-Cancer Atlas (PCA) activities, which include reviewing and regulating financial expenditures, creating and preparing necessary reports, internal and external communications, research coordination, and ensuring compliance with all federal regulations and reporting requirements (including NIH public access policy). Thus, the core directly supports all members and organizational components of the PCA. The Administrative Core will coordinate collaborations with NCI and the HTAN. Our team has extensive experience working within NCI-funded networks. As the funded HTAN centers are developed, there will be multiple opportunities to find shared aims and potential new collaborative projects in which the Vanderbilt PCA will enthusiastically participate and even lead. The Administrative Core will also ensure full compliance with the data and resource sharing plans agreed upon with NCI and the HTAN. This will be accomplished by working closely with the Data Analysis Unit to ensure that all relevant data and tools are transferred securely and in a timely manner to the DCC. During the initial development of HTAN, the Unit Co-Leads will work closely with DCC and HTAN centers in the development of SOPs and CDEs and metadata dictionaries to be collected within the Vanderbilt PCA Adenoma Center and across the network. Based on our past experience and present shared vision, we are fully committed to the success of the PCA Center and the common success of the HTAN.

项目概要：行政核心 范德比尔特癌前阿特拉斯 (PCA) 中心的领导建立在现有的多学科团队的基础上 已经在范德比尔特大学地理标志特别研究计划上合作超过 15 年 卓越（孢子）。我们还从约翰霍普金斯大学招募了更多团队成员来完善 Atlas 构建的专业知识。每个团队成员也都拥有丰富的协作经验 跨多个研究和多个机构的研究工作。行政核心将提供 对范德比尔特 PCA 活动的主要科学监督。它将拥有主要的管理和监督 负责所有癌症前期 Atlas (PCA) 活动，其中包括审查和监管财务 支出、创建和准备必要的报告、内部和外部沟通、研究 协调，并确保遵守所有联邦法规和报告要求（包括 NIH 公共访问政策）。因此，核心直接支持 PCA 的所有成员和组织组件。 行政核心将协调与 NCI 和 HTAN 的合作。我们的团队拥有广泛的 在 NCI 资助的网络内工作的经验。随着资助的 HTAN 中心的发展，将会有 寻找共同目标和潜在新合作项目的多种机会，其中范德比尔特 PCA 会热情地参与甚至领导。行政核心还将确保完全遵守 与 NCI 和 HTAN 商定数据和资源共享计划。这将通过工作来完成 与数据分析部门密切合作，确保所有相关数据和工具均以安全的方式传输 及时向DCC报告。在 HTAN 的初始开发过程中，各单位联合领导将与 DCC 和 HTAN 中心开发 SOP 和 CDE 以及要收集的元数据字典 在范德比尔特 PCA 腺瘤中心内和整个网络内。根据我们过去的经验和 提出共同的愿景，我们完全致力于 PCA 中心的成功以及 PCA 中心的共同成功 HTAN。