Administrative Core

项目总结/摘要：行政核心 范德比尔特大学医学中心TBEL中心的领导建立在现有的多学科 在范德比尔特-英格拉姆癌症中心（VICC）GI合作超过15年的团队 卓越研究特别计划（SPORE）以及人体组织图谱网络（HTAN）， 已经存在了四年。我们还聘请了约翰霍普金斯大学的辛西娅·西尔斯博士 专业知识为这个应用程序。每个团队成员在合作研究方面也有丰富的经验 在多个研究和多个机构中。行政核心将提供主要的科学 监督范德比尔特的TBEL活动。它将对所有人承担主要的管理和监督责任 TBEL活动，包括审查和管理财务支出，创建和准备必要的 报告，内部和外部沟通，研究协调，并确保遵守所有联邦 法规和报告要求（包括NIH公共访问政策）。因此，行政核心 直接支持TBEL中心的所有成员和组织组成部分，包括三个项目 以及两个核心-人类癌前模型（HPM）核心和定量生物科学核心（QBC）。 行政核心将协调与NCI和其他TBEL中心的合作。我们的团队拥有广泛的 在NCI资助的网络中工作的经验。随着资助的TBEL中心的发展， 有多种机会找到共同的目标和潜在的新的合作项目，其中范德比尔特TBEL 积极参与，甚至是领导。行政核心还将确保充分遵守 与NCI和TBEL中心商定的数据和资源共享计划。这将通过 与QBC密切合作，确保所有相关数据和工具安全、及时地传输 TBL数据协调中心。在TBEL中心的初期开发期间，该项目 核心领导和共同领导将与NCI和其他TBEL中心密切合作。根据我们过去 凭借丰富的经验和共同的愿景，我们将全力推动TBEL中心的成功。

PROJECT SUMMARY/ABSTRACT: Administrative Core The leadership of the Vanderbilt University Medical Center TBEL Center builds on an existing multidisciplinary team that has been working together for over 15 years on the Vanderbilt-Ingram Cancer Center (VICC) GI Special Programs of Research Excellence (SPORE), as well as the Human Tissue Atlas Network (HTAN) that has been in existence for four years. We have also recruited Dr. Cynthia Sears from Johns Hopkins to round out expertise for this application. Each team member also has extensive experience in collaborative research efforts across multiple studies and multiple institutions. The Administrative Core will provide the primary scientific oversight for the Vanderbilt TBEL activities. It will have primary management and oversight responsibility for all TBEL activities, which include reviewing and regulating financial expenditures, creating and preparing necessary reports, internal and external communications, research coordination, and ensuring compliance with all federal regulations and reporting requirements (including NIH public access policy). Thus, the Administrative Core directly supports all members and organizational components of the TBEL Center, including the three Projects and the two Cores - the Human Pre-Cancer Models (HPM) Core and the Quantitative Bioscience Core (QBC). The Administrative Core will coordinate collaborations with NCI and other TBEL Centers. Our team has extensive experience working within NCI-funded networks. As the funded TBEL Centers are developed, there will be multiple opportunities to find shared aims and potential new collaborative projects in which the Vanderbilt TBEL will enthusiastically participate and even lead. The Administrative Core will also ensure full compliance with the data and resource sharing plans agreed upon with NCI and the TBEL Centers. This will be accomplished by working closely with the QBC to ensure that all relevant data and tools are transferred securely and in a timely manner to the TBEL data coordinating center. During the initial development of the TBEL Center, the Project and Core Leads and Co-Leads will work closely with NCI and the other TBEL Centers. Based on our past experience and present shared vision, we are fully committed to the success of the TBEL Center.