DNA data development for cancer cell lines and patients

该项目在DNA拷贝数、甲基化和突变领域提供了特别丰富的信息，包括约1，600个细胞系和186名患者的基因和全基因组数据。以网络应用程序的形式对数据进行标准化和展示，使非生物信息学家可以访问。细胞系工作在患者之前完成，因此进一步开发。患者数据目前位于内部网站。该数据库允许多种形式的比较表型，分子或药理学模式。数据作为对查询的响应或全部提供给用户。细胞系数据可通过我们的CellMiner（用于NCI-60）或CellMinerCDB基于网络的应用程序访问。该项目旨在促进更多的科学分析，工具开发和手稿出版。

This project is particularly informative in the area of DNA copy number, methylation and mutation, including gene and whole genome data for some 1,600 cell lines and 186 patients. The standardization and presentation of the data in the form of a web-application makes it accessible for non-bioinformaticians. The cell line work was done prior to the patient and thus is further developed. The patient data currently resides on an internal site. The database allows multiple forms of comparisons to phenotypic, molecular, or pharmacological patterns. Data is being provided to the user as response to queries or in toto. The cell line data is accessible through our CellMiner (for the NCI-60) or CellMinerCDB web-based applications. The project is meant to facilitate additional scientific analysis, tool development, and manuscript publication.