Ecological and Evolutionary Functional Genomics

生态和进化功能基因组学

• 批准号: 7669943
• 负责人: SCOTT V. EDWARDS
• 金额: $ 1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-06-01 至 2010-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7669943
• 关键词: Area; Communicable Diseases; Communities; Developmental Biology; Drosophila genus; Ecology; Evolution; Foundations; Funding; Genes; Genetic; Genetic Structures; Genetic Variation; Genome; Genomics; Goals; Health; Hereditary Disease; Human; Illinois; Metagenomics; Modeling; New Hampshire; Population; Recording of previous events; Request for Proposals; Research; Research Personnel; Schools; Science; Secure; Source; Universities; Yeasts; biological adaptation to stress; comparative; functional genomics; infectious disease evolution; meetings; professor; public health relevance; symposium

DESCRIPTION (provided by applicant): This proposal requests partial funding for the upcoming Gordon Research Conference (GRC) in Ecological and Evolutionary Functional Genomics (EEFG), to be held at the Tilton School in Tilton, New Hampshire, July 12-17, 2009. The long-term goal of the conference is to catalyze interdisciplinary interactions between researchers spanning the areas of ecology, evolution and genomics. The specific aims of this proposal are to convene a diverse group of 25-30 speakers, and a total of 135 conference attendees for this five-day interactive meeting. We have already secured the commitment of Professor Gene Robinson (University of Illinois), the leader of the honeybee genome project, as a keynote, plenary speaker. In addition we plan to have sessions focusing on the following topic areas: Evolution of infectious disease, Population genomics, Evolutionary developmental biology, Ecological genomics and stress response, Community Genomics/Metagenomics, Comparative Genomics, among several others. The significance of this proposal is that it will comprise a critical component of our overall funding strategy for this meeting, which involves applications to the National Science Foundation, private companies and other sources. This application has relevance to human health because it will include speakers and session on human population genomics and demographic history, which are critical to understand the structure of genetic variation in humans, and, by extension, the genetic context in which congenital and infectious diseases arise and spread throughout the species. Public Health Relevance: The health relatedness of this application is that the meeting to be funded will include speakers and sessions on human population genomics and demographic history, which are critical to understand the structure of genetic variation in humans, and, by extension, the genetic context in which congenital and infectious diseases arise and spread throughout the species. The meeting will also include a number of talks and sessions on the evolutionary genomics of model species, such as yeast and Drosophila. Studies on such species have historically been very important for furthering the study of human evolutionary genetics and disease, and for pointing the way for similar studies on humans.

描述(由申请人提供)：本提案要求为即将举行的生态和进化功能基因组学(EEFG)戈登研究会议(GRC)提供部分资金，该会议将于2009年7月12-17日在新罕布夏州蒂尔顿的Tilton School举行。会议的长期目标是促进生态、进化和基因组学领域的研究人员之间的跨学科互动。这项提议的具体目标是召集一个由25-30名演讲者组成的不同群体，以及总共135名与会者参加这次为期五天的互动会议。我们已经获得了吉恩·罗宾逊教授(伊利诺伊大学)的承诺，他是蜜蜂基因组项目的领导者，作为主旨发言人和全体演讲人。此外，我们还计划举办以下主题的会议：传染病的进化、人口基因组学、进化发育生物学、生态基因组学和压力反应、社区基因组学/元基因组学、比较基因组学等。这项建议的意义在于，它将是我们本次会议总体筹资战略的关键组成部分，涉及向国家科学基金会、私营公司和其他来源提出的申请。这一应用程序与人类健康有关，因为它将包括关于人类种群基因组学和人口学历史的演讲者和会议，这对于了解人类遗传变异的结构，进而了解先天性和传染性疾病在整个物种中产生和传播的遗传背景至关重要。 公共卫生相关性：这项申请的健康相关性是，将得到资助的会议将包括关于人类种群基因组学和人口学历史的演讲和会议，这对了解人类遗传变异的结构，进而了解先天性和传染性疾病在整个物种中产生和传播的遗传背景至关重要。会议还将包括一系列关于模式物种进化基因组学的讲座和会议，如酵母和果蝇。从历史上看，对这类物种的研究对于进一步研究人类进化遗传学和疾病，以及为类似的人类研究指明了方向，都是非常重要的。