Ecological and Evolutionary Functional Genomics

描述（由申请人提供）：本提案要求为即将于2009年7月12日至17日在新罕布什尔州蒂尔顿的蒂尔顿学院举行的生态和进化功能基因组学（EEFG）戈登研究会议（GRC）提供部分资金。会议的长期目标是促进跨越生态学、进化和基因组学领域的研究人员之间的跨学科互动。该提案的具体目标是召集由25-30名发言者组成的多样化群体，以及135名会议与会者参加为期五天的互动会议。我们已经确保了吉恩·罗宾逊教授（伊利诺伊大学）的承诺，他是蜜蜂基因组计划的领导者，作为主题演讲，全体会议发言人。此外，我们计划举行会议，重点关注以下主题领域：传染病的进化，人口基因组学，进化发育生物学，生态基因组学和应激反应，社区基因组学/宏基因组学，比较基因组学等。该提案的重要性在于，它将构成我们本次会议总体资助战略的关键组成部分，该战略涉及向国家科学基金会、私人公司和其他来源提出申请。这一应用与人类健康有关，因为它将包括关于人类种群基因组学和人口统计学历史的演讲者和会议，这对于了解人类遗传变异的结构至关重要，进而了解先天性疾病和传染病在整个物种中产生和传播的遗传背景。

DESCRIPTION (provided by applicant): This proposal requests partial funding for the upcoming Gordon Research Conference (GRC) in Ecological and Evolutionary Functional Genomics (EEFG), to be held at the Tilton School in Tilton, New Hampshire, July 12-17, 2009. The long-term goal of the conference is to catalyze interdisciplinary interactions between researchers spanning the areas of ecology, evolution and genomics. The specific aims of this proposal are to convene a diverse group of 25-30 speakers, and a total of 135 conference attendees for this five-day interactive meeting. We have already secured the commitment of Professor Gene Robinson (University of Illinois), the leader of the honeybee genome project, as a keynote, plenary speaker. In addition we plan to have sessions focusing on the following topic areas: Evolution of infectious disease, Population genomics, Evolutionary developmental biology, Ecological genomics and stress response, Community Genomics/Metagenomics, Comparative Genomics, among several others. The significance of this proposal is that it will comprise a critical component of our overall funding strategy for this meeting, which involves applications to the National Science Foundation, private companies and other sources. This application has relevance to human health because it will include speakers and session on human population genomics and demographic history, which are critical to understand the structure of genetic variation in humans, and, by extension, the genetic context in which congenital and infectious diseases arise and spread throughout the species. Public Health Relevance: The health relatedness of this application is that the meeting to be funded will include speakers and sessions on human population genomics and demographic history, which are critical to understand the structure of genetic variation in humans, and, by extension, the genetic context in which congenital and infectious diseases arise and spread throughout the species. The meeting will also include a number of talks and sessions on the evolutionary genomics of model species, such as yeast and Drosophila. Studies on such species have historically been very important for furthering the study of human evolutionary genetics and disease, and for pointing the way for similar studies on humans.