End of Life Service Indicator

寿命终止服务指示器

• 批准号: 7747597
• 负责人: GIRISH SRINIVAS
• 金额: $ 10万
• 依托单位: TDA RESEARCH, INC.
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7747597
• 关键词: End; Life; Service; Indicator

DESCRIPTION (provided by applicant): First responders and chemical workers must be able to function in environments where chemical hazards are present. Industrial workers need protection against hazardous chemicals used in the workplace and HAZMAT personnel need respiratory protection when dealing with chemical spills, methamphetamine labs, and other cleanup operations. In the event of exposure to chemical vapors/gases from an industrial or environmental accident, respiratory protection is particularly important. The modern gas mask has a vapor tight polymer face piece that is equipped with windows and a cartridge containing activated carbon that filters the inhaled air. Most modern masks have a check valve so that exhaled air passes out of the valve rather than back through the activated carbon cartridge. As air is inhaled through the activated carbon in the cartridge, hazardous contaminants physically adsorb on the carbon surface, and because activated carbons can have surface areas of 1000 m2/g or greater, reasonably large amounts of contaminants can be removed with a single cartridge. To date, no simple technology has been developed that allows the user to determine if the chemical protection capability of a respirator cartridge has been reduced by exposure during storage, or by saturation with gases while it is in use. What is needed is a simple device that indicates the expiration of a respirator cartridge. This device would be a permanent part of a respirator cartridge integrated into the cartridge during manufacturing. Since the device is incorporated into the respirator cartridge during manufacture, the indicating device can be certified by NIOSH, and thus used by first responders. TDA proposes to develop an end of service life indicator (ESLI) that can be incorporated into a first responder chemical hazard respirator cartridge. PUBLIC HEALTH RELEVANCE: There is no simple technology has been developed that allows the first responder to determine if the chemical protection capability of a respirator cartridge has been reduced by exposure during storage, or by saturation with gases while it is in use. What is needed is a simple device that indicates the expiration of a respirator cartridge. This device would be a permanent part of a respirator cartridge integrated into the cartridge during manufacturing. Since the device is incorporated into the respirator cartridge during manufacture, the indicating device can be certified by NIOSH, and thus used by first responders. TDA proposes to develop an end of service life indicator (ESLI) that can be incorporated into a first responder chemical hazard respirator cartridge. In order to accomplish these goals in the proposed Phase I project, TDA proposes to build a test apparatus that permits us to generate precise and verifiable concentrations of challenge agents for testing the indicator, prepare indicator test strips on a porous support material, test indicator sensitivity using a variety of challenge vapors at different concentrations, temperatures, and relative humidities, in collaboration with our manufacturing partner, construct and test a prototype device, and perform an engineering analysis to estimate the costs of manufacturing commercial units.

描述（由申请人提供）：急救人员和化学工作者必须能够在存在化学危害的环境中工作。工业工人需要防护工作场所使用的危险化学品，危险品人员在处理化学品泄漏、甲基苯丙胺实验室和其他清理作业时需要呼吸防护。如果因工业或环境事故而接触化学蒸气/气体，呼吸系统防护尤为重要。现代防毒面具有一个气密聚合物面罩，配有窗口和一个含有活性炭的滤毒盒，可过滤吸入的空气。大多数现代口罩都有一个止回阀，以便呼出的空气从阀门中排出，而不是通过活性炭滤芯返回。当空气通过滤筒中的活性炭吸入时，有害污染物会物理吸附在碳表面上，并且由于活性炭的表面积可以达到 1000 m2/g 或更大，因此单个滤筒可以去除相当大量的污染物。迄今为止，还没有开发出简单的技术来让用户确定呼吸器滤毒盒的化学防护能力是否因储存期间的暴露或使用时气体饱和而降低。我们需要的是一种指示呼吸器滤毒盒到期的简单装置。该装置将是在制造过程中集成到滤筒中的呼吸器滤筒的永久部分。由于该装置在制造过程中被合并到呼吸器滤芯中，因此该指示装置可以通过 NIOSH 认证，从而由急救人员使用。 TDA 提议开发一种使用寿命终止指示器 (ESLI)，可将其纳入急救人员化学危害呼吸器滤毒盒中。公共健康相关性：目前还没有开发出简单的技术，可以让急救人员确定呼吸器滤毒盒的化学防护能力是否因储存期间的暴露或使用时气体饱和而降低。我们需要的是一种指示呼吸器滤毒盒到期的简单装置。该装置将是在制造过程中集成到滤筒中的呼吸器滤筒的永久部分。由于该装置在制造过程中被合并到呼吸器滤芯中，因此该指示装置可以通过 NIOSH 认证，从而由急救人员使用。 TDA 提议开发一种使用寿命终止指示器 (ESLI)，可将其纳入急救人员化学危害呼吸器滤毒盒中。为了在拟议的第一阶段项目中实现这些目标，TDA 提议建造一个测试设备，使我们能够生成精确且可验证浓度的挑战试剂来测试指示剂，在多孔支撑材料上制备指示剂测试条，使用不同浓度、温度和相对湿度下的各种挑战蒸气测试指示剂灵敏度，与我们的制造合作伙伴合作，构建和测试原型设备，并执行工程 分析来估计制造商业单位的成本。