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中文摘要
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描述(由申请人提供):爱荷华州妇女生殖健康研究职业发展中心,爱荷华大学卡弗医学院妇产科系,是一个优秀的地点,以容纳妇女生殖健康研究(WRHR)职业发展中心。该应用程序利用以下具体优势:(1)爱荷华大学卡弗医学院在研究和教育方面的卓越研究环境和基础设施以及在全国的突出地位;(2)已经为年轻教师建立了一个成功的研究职业发展模式;(3)在妇产科和整个医学院建立和成功的妇女健康研究主题;(4)一个已经存在的战略研究计划将被整合到WRHR中心,(5)一位经验丰富且高素质的首席研究员Kimberly Leslie, M.D.(科罗拉多大学WRHR项目前主任,AAOGF和RSDP学者),以及一位备受赞誉的科学家和教师,Mario Ascoli博士,将担任研究主任。(6)由来自系里和整个学院的资深科学家和领导组成的令人印象深刻的骨干队伍,他们将担任导师和顾问;(7)广泛的申请者池,从中招聘,重点是一个创新的小型休假计划,从代表性不足的群体中招聘学者;(8)非常强大的机构支持,这将有助于我们的成功。两个研究领域(基础和临床)和六个规划主题,选择爱荷华州,因为爱荷华州在这些领域有世界一流的研究,由爱荷华州WRHR大学支持。研究主题为(1)癌症与激素,(2)生殖疾病流行病学,(3)遗传学与基因组学,(4)激素与信号传导,(5)宿主防御,(6)高血压与脉管系统。现已建立了一个支持基础调查和临床流行病学调查的综合人力资源规划。学者将受益于相关的教学课程以及在整个机构最好的基础和临床实验室的强化培训。爱荷华大学提出的妇女生殖健康研究中心拥有满足该方案最终目标的所有组成部分,即培养一支成功的学术研究骨干,他们将在未来的研究中脱颖而出,并扩大妇女生殖健康知识的前沿。
英文摘要
DESCRIPTION (provided by applicant): The Iowa Women's Reproductive Health Research Career Development Center, the Department of Obstetrics and Gynecology at the Carver College of Medicine, the University of Iowa, is an outstanding site to house a Women's Reproductive Health Research (WRHR) Career Development Center. This application draws upon the following specific strengths: (1) the exceptional research milieu and infrastructure as well as the national prominence of the University of Iowa Carver College of Medicine in research and education, (2) a successful model of research career development for young faculty that is already in place, (3) established and successful research themes in women's health in the department of obstetrics and gynecology and throughout the college of medicine, (4) an already existing strategic research plan that will be integrated into the WRHR Center, (5) an experienced and highly qualified Principal Investigator, Kimberly Leslie, M.D. (former WRHR Program Director at the University of Colorado and an AAOGF and RSDP scholar), and an acclaimed scientist and teacher, Mario Ascoli, Ph.D., who will serve as the Research Director, (6) an impressive cadre of senior scientists and leaders from the department and throughout the college who will serve as mentors and advisors, (7) a broad based applicant pool from which to recruit with an emphasis on an innovative mini-sabbatical program to recruit scholars from underrepresented groups, and (8) very strong institutional support that will contribute to our success. Two research tracts (basic and clinical) and six programmatic themes, chosen because Iowa has world class research in these fields, are supported by the University of Iowa WRHR. The research themes are (1) cancer and hormones, (2) epidemiology of reproductive disorders, (3) genetics and genomics, (4) hormones and signaling, (5) host defense, and (6) hypertension and the vasculature. A well-integrated WRHR Program that supports both basic and clinical-epidemiologic investigation is in place. Scholars will benefit from pertinent didactic coursework along with intensive training in the finest basic and clinical laboratories throughout the institution. The University of Iowa proposed WRHR has all of the components to meet the ultimate goal of the program, to develop a successful cadre of academic investigators who will excel in research and expand the frontiers of knowledge in women's reproductive health going into the future. PUBLIC RELEVANCE: Women's reproductive health research has been stymied by a lack of trained physician scientists to enhance discovery in this important area of science. Research to ensure the best reproductive outcomes is critical to the survival of our species. The Women's Reproductive Health Research Career Development Center at the University of Iowa is now poised to recruit and train the physician investigators of the future in this field.
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Developmental Research Program
  • 批准号:
    10711641
  • 项目类别:
  • 资助金额:
    $16.04万
  • 财政年份:
    2023
  • 负责人:
    Kimberly K. Leslie
  • 依托单位:
MTDH regulates Fanconi anemia repair pathway to mediate drug resistance
  • 批准号:
    8816751
  • 项目类别:
  • 资助金额:
    $32.7万
  • 财政年份:
    2014
  • 负责人:
    Kimberly K. Leslie
  • 依托单位:
MTDH regulates Fanconi anemia repair pathway to mediate drug resistance
  • 批准号:
    8929175
  • 项目类别:
  • 资助金额:
    $31.42万
  • 财政年份:
    2014
  • 负责人:
    Kimberly K. Leslie
  • 依托单位:
MTDH regulates Fanconi anemia repair pathway to mediate drug resistance
  • 批准号:
    9331485
  • 项目类别:
  • 资助金额:
    $31.36万
  • 财政年份:
    2014
  • 负责人:
    Kimberly K. Leslie
  • 依托单位:
国内基金
海外基金
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data