The Iowa Women's Reproductive Health Research Career Development Center

描述(由申请者提供)：爱荷华州妇女生殖健康研究职业发展中心，爱荷华州大学卡弗医学院妇产科系，是妇女生殖健康研究(WRHR)职业发展中心的理想所在地。这项申请利用了以下具体优势：(1)特殊的研究环境和基础设施，以及爱荷华州大学卡弗医学院在研究和教育方面的全国领先地位，(2)已经为年轻教员建立了成功的研究职业发展模式，(3)在妇产科和整个医学院建立了成功的妇女健康研究主题，(4)将纳入WRHR中心的现有战略研究计划，(5)经验丰富和高素质的首席研究员金伯利·莱斯利，这是一位著名的科学家和教师，他将担任研究主任，(6)一批令人印象深刻的资深科学家和院系及学院领导，他们将担任导师和顾问，(7)基础广泛的申请者人才库，他们的招聘重点是创新的小型休假计划，以从代表性不足的群体中招聘学者，以及(8)将有助于我们成功的非常强有力的机构支持。两个研究领域(基础和临床)和六个规划主题被选择，因为爱荷华州在这些领域拥有世界级的研究，由爱荷华州大学WRHR支持。研究主题是(1)癌症和激素，(2)生殖障碍的流行病学，(3)遗传学和基因组学，(4)激素和信号，(5)宿主防御，(6)高血压和血管系统。一个整合良好的支持基础和临床流行病学调查的WRHR计划已经到位。学者将受益于有针对性的教学课程，以及在整个机构最好的基础和临床实验室进行的强化培训。爱荷华大学提出的WRHR具备实现该计划最终目标的所有要素，即培养一支成功的学术研究干部队伍，他们将在研究方面出类拔萃，并在未来扩大女性生殖健康的知识前沿。 公共相关性：由于缺乏训练有素的内科科学家来加强这一重要科学领域的发现，妇女的生殖健康研究一直受到阻碍。确保最佳繁殖结果的研究对我们物种的生存至关重要。爱荷华大学妇女生殖健康研究职业发展中心现在正准备招募和培训这一领域未来的内科研究人员。

DESCRIPTION (provided by applicant): The Iowa Women's Reproductive Health Research Career Development Center, the Department of Obstetrics and Gynecology at the Carver College of Medicine, the University of Iowa, is an outstanding site to house a Women's Reproductive Health Research (WRHR) Career Development Center. This application draws upon the following specific strengths: (1) the exceptional research milieu and infrastructure as well as the national prominence of the University of Iowa Carver College of Medicine in research and education, (2) a successful model of research career development for young faculty that is already in place, (3) established and successful research themes in women's health in the department of obstetrics and gynecology and throughout the college of medicine, (4) an already existing strategic research plan that will be integrated into the WRHR Center, (5) an experienced and highly qualified Principal Investigator, Kimberly Leslie, M.D. (former WRHR Program Director at the University of Colorado and an AAOGF and RSDP scholar), and an acclaimed scientist and teacher, Mario Ascoli, Ph.D., who will serve as the Research Director, (6) an impressive cadre of senior scientists and leaders from the department and throughout the college who will serve as mentors and advisors, (7) a broad based applicant pool from which to recruit with an emphasis on an innovative mini-sabbatical program to recruit scholars from underrepresented groups, and (8) very strong institutional support that will contribute to our success. Two research tracts (basic and clinical) and six programmatic themes, chosen because Iowa has world class research in these fields, are supported by the University of Iowa WRHR. The research themes are (1) cancer and hormones, (2) epidemiology of reproductive disorders, (3) genetics and genomics, (4) hormones and signaling, (5) host defense, and (6) hypertension and the vasculature. A well-integrated WRHR Program that supports both basic and clinical-epidemiologic investigation is in place. Scholars will benefit from pertinent didactic coursework along with intensive training in the finest basic and clinical laboratories throughout the institution. The University of Iowa proposed WRHR has all of the components to meet the ultimate goal of the program, to develop a successful cadre of academic investigators who will excel in research and expand the frontiers of knowledge in women's reproductive health going into the future. PUBLIC RELEVANCE: Women's reproductive health research has been stymied by a lack of trained physician scientists to enhance discovery in this important area of science. Research to ensure the best reproductive outcomes is critical to the survival of our species. The Women's Reproductive Health Research Career Development Center at the University of Iowa is now poised to recruit and train the physician investigators of the future in this field.