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中文摘要
翻译
癌症预防和人口科学(CPPS)研究计划是三个已建立的 德克萨斯健康大学癌症治疗与研究中心(CTRC)的研究计划 圣安东尼奥科学中心(UTHSCSA),有17名成员(13名小学,4名中学),他们是 重点关注并在影响南部圣安东尼奥居民的癌症预防方面取得了长足进展 德克萨斯,还有整个国家。CPPS计划的主要研究主题是:消除与癌症相关的健康 差距,特别是在该地区以拉丁裔为主的人口中;利用癌症控制来改善 成果,特别是侧重于儿童、青少年和年轻人;并确定决定因素 癌症与癌症风险和预后的关系,特别是关注前列腺癌。CPP成员拥有 在这些领域取得的几项重要成就:发展国家研究、培训和认识 拉丁美洲癌症网络;在儿童和拉丁美洲人中促进烟草预防和戒烟; 开发几个患者导航程序,以增加拉美裔人获得癌症护理的机会;测试视频 游戏技术,提高青少年对指定癌症治疗方案的依从性 评估拉丁美洲人肥胖与儿童急性淋巴细胞性白血病的关系; 创建前列腺癌风险计算器工具;以及识别前列腺癌和其他疾病的风险生物标志物 癌症。项目成员来自广泛的科学背景,如行为科学, 流行病学,基础科学,化学预防,以及UTHSCSA许多部门和 学校。CPPS研究人员在该计划内和整个CTRC内协作进行翻译 他们从实验室/诊所和基于人群的研究中获得的癌症预防结果将带来改进 减少癌症的方法,早期发现,诊断,治疗和生存到南得克萨斯州和 国家。该计划以几个多调查员项目为特色,包括一个U10和几个U01赠款,如 以及42个总体项目,其中19个项目是由NCL提供的年度指导资金超过550万美元。 教育和培训是另一个重要的方案组成部分,在会员中都是如此(通过定期 国家方案方案成员会议和癌症预防/控制客座讲师)和项目,包括 旨在培训少数民族进行研究并帮助他们在与癌症有关的领域发展的项目 博士级别。总而言之,CPPS计划是一个高度整合的多学科协作努力 不同学科之间的科学家专注于癌症的预防和控制。
英文摘要
The Cancer Prevention and Population Science (CPPS) research program, one of the three established research programs of the Cancer Therapy & Research Center (CTRC) at The University of Texas Health Science Center at San Antonio (UTHSCSA), has 17 members (13 primary, four secondary) who are focused on, and have made great strides in cancer prevention affecting the residents of San Antonio, South Texas, and the nation. The CPPS Program's key research themes are: eliminating cancer-related health disparities, especially among the region's predominantly Latino population; using cancer control to improve outcomes, especially focusing on children, adolescents, and young adults; and identifying the determinants of cancer and cancer risk and prognosis, especially focusing on prostate cancer. CPPS members have several vital accomplishments in these areas: developing a national research, training, and awareness network on Latino cancer; promoting tobacco prevention and cessation among children and Latinos; developing several patient navigation programs to increase Latino access to cancer care; testing video game technology to improve adherence to prescribed cancer treatment regimens for adolescents and young adults; assessing the relationship between obesity and childhood acute lymphoblastic leukemia in Latinos; creating a prostate cancer risk calculator tool; and identification of risk biomarkers for prostate and other cancers. Program members come from broad scientific backgrounds, such as behavioral science, epidemiology, basic science, chemoprevention, and others across many UTHSCSA departments and schools. CPPS researchers work collaboratively within the program and across the entire CTRC to translate their cancer prevention findings from the laboratory/clinic and population-based studies to bring improved methods of cancer reduction, early detection, diagnosis, treatment, and survival to South Texas and the nation. The program features severarmulti-Investigator projects, including a U10 and several U01 grants, as well as 42 overall projects, 19 of which are NCl-funded at more than $5.5 million in annual directs. Education and training is another important program component, both among membership (through regular CPPS member meetings and cancer prevention/control guest lecturers) and in projects, including several projects geared to training minorities in research and aiding their development in cancer-related fields at the doctoral level. In summary, the CPPS Program is a highly integrated multidisciplinary collaborative effort between diverse disciplines of scientists focused on cancer prevention and control.
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Bladder cancer PD-L1 control of homologous recombination: Basic mechanisms applied to novel treatments
  • 批准号:
    10467877
  • 项目类别:
  • 资助金额:
    $64.67万
  • 财政年份:
    2022
  • 负责人:
    Tyler J. Curiel
  • 依托单位:
Bladder cancer PD-L1 control of homologous recombination: Basic mechanisms applied to novel treatments
  • 批准号:
    10688261
  • 项目类别:
  • 资助金额:
    $62.07万
  • 财政年份:
    2022
  • 负责人:
    Tyler J. Curiel
  • 依托单位:
Regulation of ER-beta Signaling in Carcinogenesis
  • 批准号:
    10092967
  • 项目类别:
  • 资助金额:
    $48.43万
  • 财政年份:
    2019
  • 负责人:
    Tyler J. Curiel
  • 依托单位:
(PQ2) PD-L1/PD-1 signals in aged hosts undergoing cancer immunotherapy
海外基金