Immune Tolerance Network: Type 1 diabetes
Immune Tolerance Network: Type 1 diabetes
批准号:
8147301
负责人:
JEFFREY BLUESTONE
金额:
$1256.93万
依托单位国家:
美国
项目类别:
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-09-30 至 2014-04-30
中文摘要
免疫耐受网络致力于新的耐受诱导疗法的临床评估,这些疗法将重新教育免疫系统以消除有害的免疫反应。ITN正在进行自身免疫性疾病的临床试验,如1型糖尿病。此外,为了了解候选疗法的潜在作用机制并监测耐受性,ITN建立了最先进的核心实验室设施,以进行综合机制研究和临床研究,开发和评价标记物和测定法,以测量人类耐受性的诱导、维持和丧失。
英文摘要
The Immune Tolerance Network is dedicated to the clinical evaluation of novel tolerance-inducing therapies that will ¿re-educate¿ the immune system to eliminate injurious immune responses. The ITN is conducting clinical trials in autoimmune diseases such as Type 1 Diabetes. In addition, to understand the underlying mechanisms of action of the candidate therapies and to monitor tolerance, the ITN has established state of the art core laboratory facilities to conduct integrated mechanistic studies and clinical research to develop and evaluate markers and assays to measure induction, maintenance, and loss of tolerance in humans.
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会议论文
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依托单位:
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依托单位:--
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依托单位:
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依托单位:--
国内基金
海外基金
Autoimmune diseases therapies: variations on the microbiome in rheumatoid arthritis
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批准号:31171277
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项目类别:面上项目
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资助金额:60.0万元
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批准年份:2011
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负责人:Christine Nardini
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依托单位: