Immune Tolerance Network: Food Allergy

免疫耐受网络（ITN）致力于新的耐受诱导疗法的临床评估，这些疗法将重新教育免疫系统以消除有害的免疫反应。ITN对包括过敏性疾病，特别是食物过敏在内的疾病进行临床试验。此外，为了了解候选疗法的潜在作用机制并监测耐受性，ITN建立了最先进的核心实验室设施，以进行综合机制研究和临床研究，并开发和评估标记物和测定法，以测量人类耐受性的诱导、维持和丧失。年龄在1岁以下至7岁之间的儿童是正在进行的临床试验的参与者。

The Immune Tolerance Network (ITN) is dedicated to the clinical evaluation of novel tolerance-inducing therapies that will ¿re-educate¿ the immune system to eliminate injurious immune responses. The ITN conducts clinical trials in diseases that include allergic diseases, particulary food allergy. In addition, to understand the underlying mechanisms of action of the candidate therapies and to monitor tolerance, the ITN has established state of the art core laboratory facilities to conduct integrated mechanistic studies and clinical research, and to develop and evaluate markers and assays to measure induction, maintenance, and loss of tolerance in humans. Children between the ages of less than one year old to 7 years old are participants in an ongoing clinical trial.