Developmental Core

发展核心的总体目标是吸引新的调查人员和培养新的飞行员 神经艾滋病问题的研究和方法，也基于复杂的假设和方法 作为高质量的试点数据，是制定具有足够竞争力的项目提案所必需的 确保获得外部资金。在当前的供资周期中，通过其发展赠款方案， 发展核心已经授予了16项发展赠款，所有这些都包含了有希望的新方向 神经艾滋病研究，面向学生、博士后研究员、初级和高级教职员工，包括 来自巴西的国际研究员。此外，16名初级研究人员通过 导师调查员计划，74名不同级别的学员在HNRC的实验室轮换 联合调查员。到目前为止，这笔种子资金已经产生了12项由调查员发起的同行审查 提案，其中7个提案迄今已获得资金。与HNRC调查人员合作的实习生与人合著了 83份原创项目出版物(另外7份已提交)；7本书章节，67份 会议报告。我们更新的目标是协同增加容量和 通过(1)交叉活动实施发展助学金和指导性研究人员方案的有效性 与新提议的国际核心，旨在指导国际调查人员和 加强外部支持创新的国际研究或项目的潜力；和(2) 美国国立卫生研究院为神经艾滋病博士后和博士后研究人员提交的T32培训计划 及其附属实验室，旨在吸引顶尖实习生(特别是任职人数不足的 (少数族裔)和促进神经行为和神经医学科学的职业发展。使用它的 多学科的研究环境，有才华和生产力的研究人员，高度有组织和 集成的基础设施，以及丰富的纵向样本和数据库，HNRC处于有利地位 发展和支持更多的创新研究机会，通过促进初步研究和 指导来自多个学科的受训人员。

The overall aim of the Developmental Core is to attract new investigators and to foster novel pilot studies and approaches to neuroAIDS questions, based on sophisticated hypotheses and methods, as well as quality pilot data, requisite to the development of project proposals that are sufficiently competitive to secure extramural funding. In the current funding cycle, through its Developmental Grants program, the Developmental Core has awarded 16 developmental grants, all encompassing promising new directions in neuroAIDS research, to students, postdoctoral fellows, and junior and senior faculty, including an international fellow from Brazil. In addition, 16 junior researchers have received support through the Mentored Investigator Program, and 74 trainees of various levels have rotated through labs of the HNRC associated investigators. This seed funding has so far produced 12 investigator-initiated peer review proposals, 7 of which have been funded to date. Trainees working with the HNRC investigators have co-authored 83 original project publications (and an additional 7 in submission); 7 book chapters, and 67 conference presentations. Our aims for the renewal are to augment synergistically the capacity and effectiveness of the Developmental Grants and Mentored Investigator Programs via (1) crossover activities with the newly proposed International Core, designed for mentoring international investigators and enhancing the potential for extramural support of innovative international research or projects; and (2), submission of an NIH T32 training program for pre- and postdoctoral neuroAIDS researchers at the HNRC and its affiliate laboratories, aimed toward attracting top-notch trainees (in particular, underrepresented minorities) and promoting careers in the neurobehavioral and neuromedical sciences. With its multidisciplinary research environment, talented and productive research staff, highly organized and integrated infrastructure, and rich longitudinal specimen and data banks, the HNRC is well-positioned to develop and support expanded opportunities for innovative research by fostering preliminary studies and mentoring of trainees from a wide array of disciplines.