CNS HIV ANTI-RETROVIRAL THERAPY EFFECTS RESEARCH (CHARTER) EXTENSION

CNS HIV 抗逆转录病毒治疗效果研究（章程）扩展

• 批准号: 8335731
• 负责人: IGOR GRANT
• 金额: $ 145.12万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-16 至 2015-09-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8335731
• 关键词: AIDS neuropathy; Address; Anti-Retroviral Agents; Biological Preservation; Blood; Brain; California; Cells; Cognition; DNA; Disease; Evolution; Failure; Funding; Goals; HIV; Highly Active Antiretroviral Therapy; Image; Impaired cognition; Individual; Laboratories; Light; MRI Scans; Magnetic Resonance Imaging; Medical; Morbidity - disease rate; Nerve Fibers; Nervous System Trauma; Nervous system structure; Neurocognitive; Neurologic; Neuropathy; Participant; Performance; Peripheral Nervous System Diseases; Plasma; Population; Procedures; Protocols documentation; RNA; Research; Research Personnel; Research Project Grants; Role; Schwann Cells; Site; Texas; Universities; Washington; antiretroviral therapy; base; cohort; density; follow-up; medical schools; mortality; neuropsychological; performance site; quality assurance; virus genetics; white matter

This CNS HIV Antiretroviral Therapy Effects Research Extension (CHARTER Extension) is a continuation of the epidemiological longitudinal study of the participants being studied under the existing award, N01MH22005, entitled, ¿CNS HIV Antiretroviral Therapy Effects Research (CHARTER)¿, which was awarded to the University of California at San Diego (UCSD) in September 2002. This contract is due to expire on August 31, 2010. This follow-on study to CHARTER is expected to collect valuable research data over the course of the next 5 years, such as neuromedical characterization, neuropsychological functioning, psychiatric and drug abuse variables, treatment data, various brain imaging results, and viral and host genetics information from specific groups of subjects. This data will ultimately be included with the accumulated clinical and research data stored.

中枢神经系统HIV抗逆转录病毒治疗效果研究延伸 (宪章扩展)是根据现有奖项N01MH2 2005对参与者进行的流行病学纵向研究的继续，该奖项于2002年9月授予加州大学圣地亚哥分校(UCSD)，题为CNS艾滋病毒抗逆转录病毒治疗效果研究(CHECURE)。这份合同将于2010年8月31日到期。 Charge的这项后续研究预计将在未来5年内收集有价值的研究数据，如神经医学特征、神经心理功能、精神和药物滥用变量、治疗数据、各种脑成像结果以及来自特定受试者组的病毒和宿主遗传学信息。这些数据最终将包括在存储的累积临床和研究数据中。