Liver Growth, Injury and Metabolism: Basic and Applied Biology

描述（由申请人提供）：目前申请为美国实验生物学学会联合会（FASEB）夏季研究会议“肝脏生长，损伤和代谢：基础和应用生物学”寻求部分支持。在过去的20年里，这个会议每两年举行一次，现在被认为是世界上最重要的会议，涵盖了涉及肝脏的所有基础科学研究。会议将于2010年8月15日至20日在科罗拉多州斯诺马斯举行。会议的主要目标是：1)整合肝脏生物学不同领域的研究进展，以促进国内和国际规模的新合作项目；2)鼓励初级和早期研究人员；妇女和少数民族科学家从事肝脏研究，以确保肝病和生物学研究保持活力；iii)通过基础和临床研究人员的相互作用，加速将肝脏生物学的基本进展转化为新的临床治疗方法。这些目标将通过具体的方案战略来实现。该计划分为九个主要会议，包括42位受邀演讲者的演讲。此外，这些会议将容纳多个简短的“最新”演讲，这些演讲将被选中代表肝脏研究中最重要和最及时的研究进展。将优先考虑初级、少数民族和女性调查员。该项目还提供了两个海报环节进行一对一的对话，并在整个停留期间为演讲者和与会者提供了一些非正式但亲密的科学交流机会。具体的会议主题包括肝脏分化和器官发生，健康和疾病中的肝胆基因表达调节，肝脏生长和再生，健康和疾病中的肝脏代谢，肝损伤和肝纤维化，肝癌，肝干细胞及其对再生医学和发展的影响，肝细胞移植和肝组织工程以及基础和转化肝脏病理生物学的最新进展。因此，该计划整合了肝脏健康和疾病基础和应用方面最相关和最及时的主题，以促进科学交流，传播，教育和合作和翻译。

DESCRIPTION (provided by applicant): The current application seeks partial support for the Federation of American Societies for Experimental Biology (FASEB) summer research conference on "Liver Growth, Injury and Metabolism: Basic and Applied Biology". For the past 20 years, this meeting has been held biennially and is now recognized as the world's premier conference covering all aspects of basic science research involving the liver. The conference will be held from August 15th to 20th, 2010 in Snowmass, Colorado. The main goals of the conference are to i) integrate the research advances offered by disparate areas of liver biology in order to foster new collaborative projects on both national and international scale, ii) encourage junior and early stage investigators, women and minority scientists to pursue liver research to ensure that the study of hepatic disease and biology remains vigorous and iii) accelerate translation of fundamental advances in liver biology into novel clinical treatments through the interactions of basic and clinical researchers. These goals will be achieved through specific programmatic strategies. The program is divided into nine major sessions and includes presentations from forty-two invited speakers. In addition, these sessions will accommodate multiple short 'late-breaking' talks that will be chosen to represent the most significant and timely research advances in liver research. Preference will be given to junior, minority and women investigators. The program also provides two poster sessions for one-on-one dialogue and several additional opportunities for informal, yet intimate scientific exchange among speakers and attendees throughout the stay. Specific session topics include liver differentiation and organogenesis, regulation of hepatobiliary gene expression in health and disease, liver growth and regeneration, liver metabolism in health and disease, liver injury and hepatic fibrosis, liver cancer, liver stem cells and implications in regenerative medicine and development, hepatocyte transplantation and hepatic tissue engineering and recent advances in basic and translational liver pathobiology. Thus, the program amalgamates the most relevant and timely topics in basic and applied aspects of liver health and disease to promote scientific exchange, dissemination, education and collaboration and translation. PUBLIC HEALTH RELEVANCE: Narrative The FASEB summer research conference on "Liver Growth, Injury and Metabolism: Basic and Applied Biology" is the premier international conference on basic and translational research in liver biology. The meeting has been held for the last 20 years and historically has been attended by 180 - 200 investigators. The past success and excellence of the meeting has resulted in a central group of approximately 80 scientists who attend regularly. Many of these scientists form the core of basic liver research in the U.S.A., and represent the thought-leaders in the field. The meeting also attracts many junior investigators, who are given the opportunity to present their research and enhances networking. Other participants apply to broaden their understanding of liver biology or are interested in specific programmatic content. Thus, the meeting is unique in its content, at the forefront in timeliness of topics and internationally recognized premier conference in basic and translational liver biology.