2011 Annual Scientific Meeting of the International Childhood Leukemia Consortium

描述（由申请人提供） 白血病是儿童中最常见的癌症。尽管对父母和早期生活暴露的评估有所改进，但这种疾病的相对罕见性使得对环境和遗传风险因素的研究具有挑战性。 一组独立的国际研究人员建立了儿童白血病国际联盟（CLIC），以克服个体、小型研究的局限性，并支持儿童白血病病因学中因果因素的研究。 CLIC联盟的年度会议为CLIC调查人员以及其他相关方提供了一个重要的机会，以开发和讨论合作分析和未来项目。这些年度会议还提供了机会，以建立信任，尊重和来自不同国家的研究人员之间的信心;提供指导和建议，研究人员规划新的研究;并提供一个论坛，讨论，开发和追求新的研究方向。具体而言，2011年CLIC年会将为与会者提供以下机会： 1)讨论新的科学假设，遗传学研究中的尖端技术，汇总分析中的方法学问题，以及其他新出现的感兴趣的主题， 2)为所有进行合作研究的成员举办工作会议，并为儿童白血病国际流行病学研究的汇总分析提出建议; 3)开发所需的数据字典和分类系统，并对新的基于网络的互动式CLIC集中数据储存库进行beta测试; 4)与国际儿童癌症队列联盟（I4 C）正在进行的儿童白血病研究协调研究活动。 公共卫生相关性：虽然白血病是儿童中最常见的癌症，但其相对罕见性使得环境和遗传风险因素的研究具有挑战性。儿童白血病国际联盟（CLIC）由一群独立的国际研究人员组成，他们致力于汇集资源和数据，最终目标是了解儿童白血病的原因，并确定干预和预防的目标。CLIC联盟的年度会议为CLIC研究人员以及其他相关方提供了一个机会，以开发合作项目和数据分析;在来自不同国家的研究人员之间建立信任，尊重和信心;为计划新研究的研究人员提供指导和建议;并为讨论，开发和追求新的研究方向提供论坛。

DESCRIPTION (provided by applicant) Leukemia is the most commonly occurring cancer among children. Despite improved assessment of parental and early life exposures, the relative rarity of the disease makes the study of the environmental and genetic risk factors challenging. A group of independent, international researchers established the Childhood Leukemia International Consortium (CLIC) to overcome the limitations of individual, smaller studies, and support the study of causal factors in the etiology of childhood leukemia. The annual meetings of the CLIC consortium provide an important opportunity for CLIC investigators, as well as other interested parties, to develop and discuss collaborative analyses and future projects. These annual in person meetings also provide the opportunity to build trust, respect and confidence among researchers from different countries; to provide guidance and advice to researchers planning new studies; and to provide a forum for discussion, development, and pursuit of new research directions. Specifically, the 2011 CLIC Annual Meeting will provide attendees with the opportunities to: 1) Discuss novel scientific hypotheses, cutting edge techniques in genetic studies, methodologic issues in pooled analyses, and other topics of emerging interest, 2) Conduct working sessions for all members pursuing collaborative studies and develop proposals for pooled analyses from international epidemiologic studies of childhood leukemia; 3) Develop needed data dictionaries and classification systems and beta test the new web-based interactive CLIC centralized data repository; and, 4) Coordinate research activities with the childhood leukemia study being conducted by the International Childhood Cancer Cohort Consortium (I4C). Public Health Relevance: Although leukemia is the most frequent cancer occurring among children, its relative rarity makes the study of the environmental and genetic risk factors challenging. The Childhood Leukemia International Consortium (CLIC) consists of a group of independent and international researchers who are committed to pooling resources and data with the ultimate goal of understanding the causes of childhood leukemia and identifying targets for intervention and prevention. The annual meetings of the CLIC consortium provides an opportunity for CLIC investigators, as well as other interested parties, to develop collaborative projects and data analyses; build trust, respect and confidence among researchers from different countries; provide guidance and advice to researchers planning new studies; and provide a forum for discussion, development, and pursuit of new research directions.