Clinical Scholars Biomedical Research Training Program

描述（由申请人提供）：纪念斯隆-凯特琳癌症中心（MSKCC）的临床学者生物医学研究培训计划为一群杰出的医学博士或医学博士/博士提供癌症研究方面的指导实验室培训经验。该培训将为癌症生物学和临床研究领域的职业生涯做好准备。申请6个职位。这些研究员由主要研究人员进行培训，这些研究人员是从纪念斯隆-凯特琳癌症中心的专业人员中挑选出来的，他们是实验室研究人员。一个结构化和有凝聚力的两年培训计划，旨在为指导实验室研究，现代生物学和生物信息学的教学课程工作和职业发展技能提供杰出的指导。学员可以使用纪念斯隆-凯特琳癌症中心的所有资源。主要重点研究领域包括：1)细胞增殖控制的信号和途径；2)发育生物学和细胞分化的调控途径；3)细胞间相互作用、粘附和蛋白靶向；4)肿瘤免疫学、免疫治疗与移植生物学；5)人类癌症生物学、小鼠癌症模型、遗传学和分子病理学；6)药物开发和治疗。接受该项目培训的内科医生和科学家将更容易地将生物医学和癌症相关研究的最新革命性发现转化为患者护理。

DESCRIPTION (provided by applicant): The Clinical Scholars Biomedical Research Training Program at Memorial Sloan-Kettering Cancer Center (MSKCC) provides a mentored laboratory training experience in cancer research for a group of outstanding MD's or MD/PhD's. This training will prepare highly qualified physician-scientists for a career at the interface of cancer biology and clinical research. Six positions are requested. The fellows are trained by principal investigators, drawn from the professional staff of Memorial Sloan-Kettering Cancer Center who are laboratory investigators. A structured and cohesive two-year training program has been designed to provide outstanding mentorship in guided laboratory research, didactic course work in modern biology and bioinformatics and career development skills. Trainees have access to all resources of the Memorial Sloan-Kettering Cancer Center. The areas of principal emphasis for research include: 1) Signals and pathways involved in control of cell proliferation; 2) Regulatory pathways involved in developmental biology and cell differentiation; 3) Cell-cell interactions, adhesion and protein targeting; 4) Tumor immunology, immunotherapy and transplantation biology; 5) Human cancer biology, mouse models of cancer, genetics and molecular pathology; and 6) Drug development and therapeutics. Physicians-scientists receiving training from this program will be poised to more readily translate the recent revolutionary discoveries of biomedical, cancer-related research into patient care.