Chemosensory Training Program

描述(由申请者提供)：这项提案要求资金继续在佛罗里达州立大学(FSU)进行基础化学传感研究的培训计划。要求提供四个博士后职位和两个博士后职位。FSU神经科学项目在化学感觉培训项目中运作，在感觉系统，特别是化学感觉系统方面的高质量培训和研究方面有着悠久的历史。佛罗里达州立大学的培训计划坚定地把重点放在寻找基本的科学知识上，所有的应用和临床理解都必须以此为基础。它的特点是相关教员之间研究视角的多样性和研究方法的多样性，甚至在一个研究人员的实验室内也是如此。因此，该计划为博士后和博士后实习生提供了不同寻常的机会来探索和掌握许多关于化学感觉功能的重要问题的研究方法。要做到这一点，要在习惯于富有成效的合作的备受尊敬的教师的指导下进行。该计划所代表的研究方法包括电生理、分子、解剖学和定量行为分析。研究支持设施也很特别；例如，分子生物学、电子学、计算机、电子/共焦显微镜和摄影设施，以及专业人员，都可供项目成员和学员使用。自上次竞争更新以来，一名非常杰出的新教员加入了培训计划，几乎所有计划教职员工现在都在新建筑中拥有新的实验室空间。该项目的显著特点包括其杰出的历史和优秀的教师队伍，其重点是深入和广泛研究的基础机制，以及可用的卓越技术设施。受训人员有机会获得成功拓展知识边界所必需的观点，并有机会获得咨询和协助，以获得从事外部资助的生产性研究事业所需的技能。 公共卫生相关性：FSU的培训计划侧重于寻找基本的科学知识，所有的应用和临床理解都必须以此为基础。该项目为博士后和博士后实习生提供了不同寻常的机会，让他们探索和掌握许多关于味觉和嗅觉功能的重要问题的研究方法，这些问题的丧失会导致严重的生活质量损失，这些人的中枢大脑回路在进食障碍、肥胖症、糖尿病和高血压以及其他神经疾病中起着重要作用。

DESCRIPTION (provided by applicant): This proposal requests funds for continuation of a training program in fundamental chemosensory research at Florida State University (FSU). Four positions at the predoctoral level and two positions at the postdoctoral level are requested. The FSU Neuroscience Program, within which this Chemosensory Training Program operates, has a long history of high quality training and research in sensory systems, especially the chemosensory systems. The training program at FSU is firmly focused on the search for fundamental scientific knowledge, on which all applied and clinical understanding must be based. It is characterized by a diversity of research perspectives among the associated faculty and a diversity of research methodologies even within a single investigator's laboratory. Thus, the program affords pre- and post-doctoral trainees with unusual opportunities to explore and master many research approaches to important questions about chemosensory function. And to do so under the guidance of well-respected faculty used to productive collaborations. The research approaches represented in the Program include electrophysiological, molecular, anatomical, and quantitative behavioral analysis. The research support facilities are also exceptional; for example, molecular biological, electronics, computer, electron/ confocal microscopy and photography facilities, with professional staff, are all available to program members and trainees. A highly distinguished new faculty member has joined the training program since the last competitive renewal and almost all program faculties now have new laboratory space in new buildings. The notable features of this program include its distinguished history and excellent faculty, its focus on basis mechanisms studied in depth and breadth, and the outstanding technical facilities available. Trainees have an opportunity to acquire the perspective that is necessary for success in pushing out the boundaries of knowledge, and advice and assistance in obtaining the skills necessary for a career in externally funded productive research. PUBLIC HEALTH RELEVANCE: The training program at FSU is focused on the search for fundamental scientific knowledge, on which all applied and clinical understanding must be based. The program affords pre- and post-doctoral trainees with unusual opportunities to explore and master many research approaches to important questions about taste and smell function, whose loss involves devastating loss of quality of life, and whose central brain circuits are important in eating disorders, obesity, diabetes and hypertension; and perhaps other neurological disorders.