Clinical Trials Network: The Texas Node

临床试验网络：德克萨斯节点

基本信息

批准号：
9142447
负责人：
MADHUKAR H. TRIVEDI
金额：
$ 12.64万
依托单位：
UT SOUTHWESTERN MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
起止时间：
2005-09-01 至 2020-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9142447
关键词：
Academy Address Adolescent Alcohol or Other Drugs use American Analgesics Ancillary Study Area Caring Chinese People Clinic Clinical Clinical Research Clinical Trials Clinical Trials Network Collaborations Communities Community Physician Comorbidity Early Intervention Early identification Educational workshop Electronic Health Record Ensure Evidence based practice Exercise Expenditure Family Physicians Federally Qualified Health Center Foundations Funding Funding Mechanisms Future Genetic Genetic study Grant Health Health Personnel Health Sciences Health Services Health system Healthcare Hispanics Home environment Hospitals Individual Information Systems Institutes Intervention K-Series Research Career Programs Knowledge Leadership Literature Measurement Medical Medical Records Medical center Mental Depression Mental disorders Mentors Methods Minority National Institute of Drug Abuse Organizational Change Outcomes Research Outpatients Patient-Focused Outcomes Pediatric Hospitals Performance Persons Pharmaceutical Preparations Physicians Population Primary Health Care Provider Psychiatry Publications Research Research Institute Research Personnel Residencies Risk Scientist Secure Services Site Solid Substance Use Disorder System Technology Texas Training Training Activity Translational Research Universities Veterans Work addiction base candidate selection care systems career development chronic pain experience improved innovation interest medical specialties member metropolitan multi-site trial novel novel strategies patient oriented patient population practice-based research network primary care setting programs safety net screening symposium treatment center treatment program

项目摘要

DESCRIPTION: This is a competing renewal application to continue funding the Texas Node (TxN) of the NIDA Clinical Trials Network (CTN). During the previous funding period the TxN, based at the University of Texas Southwestern Medical Center in Dallas, made substantial contributions to CTN research, the scientific literature, and dissemination and training activities TxN study sites were top performers across the 8 CTN trials implemented. TxN scientists developed and led three studies: the first large study to evaluate exercise as a novel intervention for stimulant use, a genetics study, and a study using electronic health records (EHRs). Outstanding contributions to the field were made, with 38 publications and 57 presentations. Over 300 addiction treatment providers were trained in several evidence-based practices via annual workshops hosted by the TxN. Scientists mentored junior investigators, resulting in funded grants and publications. Changes made to increase efficiency, decrease expenditures, and continually improve performance during the previous funding period have uniquely prepared the TxN to perform superbly during the next period. This renewal application capitalizes on over 20 years of experience of the PI, Madhukar H. Trivedi, MD, and the experiences of other key investigators through its emphasis on primary care networks, large systems of care, and use of EHRs to positively impact substance use. Building on the TxN's solid foundation of collaborating with specialty addiction community treatment programs, additional partnerships have been secured with healthcare networks that provide access to varied patient populations throughout Texas and the US. These networks are excited to work with the TxN and the CTN. Partners include one of the largest adolescent outpatient primary care networks in the US, one of the largest safety net hospital systems in the US, and the American Academy of Family Physicians National Research Network. Other important collaborating groups include the national VA Substance Use Disorder - Quality Enhancement Research Initiative, Patient Centered Outcomes Research Institute's Greater Plains Collaborative, and the National Center for Advancing Translational Sciences Accrual for Clinical Trials. The TxN research agenda, which focuses on early identification and intervention, is consistent with the CTN's priorities, addresses clinical needs identified by node partners, and capitalizes on expertise in the TxN. The TxN aims to answer questions of critical importance to the field by utilizing innovative interventions as well as EHR- and other technology-based methods, at the point of primary care, to significantly improve the care of persons who misuse substances.

描述：这是一项竞争性续订应用程序，可继续资助NIDA临床试验网络（CTN）的德克萨斯节点（TXN）。在上一个资金期间，总部位于达拉斯西南医学中心的TXN为CTN研究，科学文献以及传播和培训活动做出了重大贡献，TXN研究站点是实施了8个CTN试验的最佳表现。 TXN科学家制定并领导了三项研究：第一项大型研究，以评估运动作为兴奋剂使用的新干预，一项遗传学研究以及使用电子健康记录（EHRS）的研究。为该领域做出了杰出的贡献，其中有38个出版物和57个演讲。通过TXN举办的年度研讨会，对几种基于证据的实践进行了多种基于证据的训练，超过300多名成瘾治疗提供者进行了培训。科学家指导了初级调查人员，从而获得了资助的赠款和出版物。在上一个融资期间，在提高效率，降低支出并不断提高绩效的变化已使TXN在下一个时期的表现出色。这种更新的应用利用了PI，Madhukar H. Trivedi的20多年经验，以及其他主要研究人员的经验，其强调其对初级保健网络，大型护理系统以及EHR的使用来积极影响药物使用。在TXN与专业成瘾社区治疗计划合作的坚实基础的基础上，与医疗网络获得了其他合作伙伴关系，这些医疗网络可为整个德克萨斯州和美国的各种患者群体提供访问。这些网络很高兴与TXN和CTN合作。合作伙伴包括美国最大的青少年门诊初级保健网络之一，美国最大的安全净医院系统之一和美国家庭医师学会国家研究网络。其他重要的合作小组包括国家VA药物使用障碍 - 质量增强研究计划，以患者为中心的成果研究所的大平原合作社以及国家推进临床试验的转化科学中心。侧重于早期识别和干预的TXN研究议程与CTN的优先级一致，它解决了节点合作伙伴确定的临床需求，并利用TXN的专家。 TXN旨在通过利用创新干预措施以及EHR和其他基于技术的方法来回答对该领域至关重要的问题，以显着改善未经物质的人的护理。