National Exposure Assessment Laboratory at Emory

埃默里国家暴露评估实验室

• 批准号: 9062180
• 负责人: MIRIAM B. VOS
• 金额: $ 78.5万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-30 至 2021-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9062180
• 关键词: Adopted; Biological; Biological Assay; Biological Markers; Biomedical Engineering; Center Core Grants; Chalk; Child; Child health care; Childhood; Clinical; Collaborations; Communities; Databases; Development; Devices; Environmental Health; Fostering; Grant; Health Sciences; Healthcare; Incubators; Informatics; Laboratories; Leadership; Life; Melissa; Methods; Modeling; National Institute of Environmental Health Sciences; Nutritional Study; Quality Control; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Rest; Science; Scientist; Series; Solutions; System; Systems Biology; Targeted Research; Techniques; Technology; Technology Transfer; Testing; Training; Validation; Work; base; design; innovation; innovative technologies; novel; novel strategies; pediatric department; programs; ranpirnase; research and development; response

The Developmental Research Resource core will be led by Melissa Kemp, a systems biologist in the Department of Biomedical Engineering at Georgia Tech, and Miriam Vos, a pediatric hepatologist, in the Department of Pediatrics at Emory. Dr. Kemp is co-director of the HERCULES Systems Biology Core and is well-connected with the environmental health science community at Emory, as well as the biomedical engineering community at Georgia Tech. Dr. Vos is Director of Graduate Studies for the Nutritional Health Sciences doctoral program and a top clinical scientist at Children’s Healthcare of Atlanta. Together, Dr. Kemp and Dr. Vos will provide enthusiastic leadership to the Development Core. The core will hold a monthly chalk talk series where investigators will share their ideas with the Development Research Resource and the rest of NEALE team, including representatives of the respective offices of technology transfer. The overall theme of the core is to foster the creation of innovative technologies and approaches for use in children’s environmental health research, including development and validation of new biomarkers, informatic solutions, and devices. The core will work closely with the Targeted Research Resource, the Untargeted Research Resource, and the Biological Response Resource to test and validate new features, biomarkers, and assays. The Development Core will focus on the following objectives: Objective 1. To identify novel and innovative approaches to assess exposures and responses in children. Objective 2. To test the feasibility of these new approaches and provide rigorous validation of the methods, tests, or platforms. Objective 3. To incorporate new approaches into the CHEAR platform. The Development Core will strive to develop and incorporate the very best science into children’s health research. We will use a design charrette model to collect input from key stakeholders as we develop and adopt new methods and technologies. We will also rely on the input of our Advisory Board, which has exceptional expertise in pediatric care and children’s health research, in identifying approaches and ideas most likely to have a major impact. The above objectives will help move the creative ideas into creative solutions.

发展研究资源核心将由梅丽莎·坎普领导，她是 佐治亚理工学院生物医学工程系和儿科肝病专家Miriam Vos在 埃默里大学儿科。坎普博士是大力神系统生物学核心的联席主任， 与埃默里的环境健康科学界以及生物医学 佐治亚理工学院的工程学社区。沃斯博士是营养健康研究生研究生部主任 他是亚特兰大儿童保健科学博士项目和顶级临床科学家。一起，坎普博士 沃斯博士将热情地领导发展核心。核心将保持每月一次的粉笔 访谈系列，调查人员将与发展研究资源和其他人分享他们的想法 尼尔团队，包括各自技术转移办公室的代表。的总主题 核心是促进创新技术和方法的创造，用于儿童 环境健康研究，包括新生物标记物的开发和验证，信息学 解决方案和设备。核心将与目标研究资源、非目标研究资源密切合作 研究资源和生物响应资源，以测试和验证新功能、生物标志物和 化验。发展核心将侧重于以下目标：目标1.确定新颖和 评估儿童暴露和反应的创新方法。目标2.测试以下项目的可行性 这些新的方法和方法提供了严格的方法、测试或平台验证。目标3.达到 将新方法纳入CHEAR平台。发展核心将努力发展和 把最好的科学融入到儿童健康研究中。我们将使用一个设计Charrette模型来 在我们开发和采用新方法和技术时，收集关键利益相关者的意见。我们还将依靠 关于我们咨询委员会的意见，该委员会在儿科保健和儿童健康方面拥有非凡的专业知识 研究，在确定最有可能产生重大影响的方法和想法方面。上述目标将 帮助将创造性的想法转化为创造性的解决方案。