Detroit Cardiovascular Training Program

描述（由申请人提供）：心血管疾病是美国死亡的主要原因。了解心脏和循环的生理和病理是改善心血管疾病治疗和预防的基础。韦恩州立大学在提供心血管科学方面的广泛培训方面有着出色的记录，在底特律大都会地区的少数民族学生培训方面也有出色的记录，在该地区的研究教育中发挥了重要作用。这项新的T32提案寻求财政支持，以加强我们在培养新一代科学家方面的研究培训工作，这些科学家不仅将从事心血管研究以改善卫生保健，而且还将通过将创新转化为医疗实践来加强我们的经济基础。该提案包括一个重点项目，以培养心血管研究方面的博士前研究生。新的底特律心血管培训计划将以14名在心血管生理学和疾病方面具有互补科学专业知识的培训教师为基础，重点培养具有心血管健康和疾病分子机制强大背景的21世纪科学家，他们配备了综合和转化的科学研究方法。这个新项目的目标是每年支持4名博士预科生。学员将从优秀的候选人中挑选，包括可能来自美国国立卫生研究院支持的最大化学生多样性倡议（IMSD）计划的未被充分代表的少数民族。除了外部资助的活跃的个人研究项目和经过验证的培训生产力之外，我们的培训教师在联合研究和培训合作方面有着悠久的历史。这种强大的研究环境使我们能够通过教学课程和指导研究的结合，在心血管科学领域提供多学科培训，包括高血压，心肌收缩性，心力衰竭，心肌缺血-再灌注损伤和心血管适应。培训计划为负责任的研究行为提供全面的教学和实践指导。职业发展培训将包括研究讨论会和讲习班，重点是写作和陈述技巧以及研究金和研究补助金的写作和评价。特殊的机构承诺到位，以支持我们的计划。项目的运作将由一个指导委员会监督，该委员会由项目主任、项目协调员和三名培训教员组成。该计划将由内部咨询委员会与外部顾问协商后定期进行审查。生理学系办公室工作人员将为该计划的人事、会计和计划运作提供行政支持。

DESCRIPTION (provided by applicant): Cardiovascular disease is a leading cause of mortality in the United States. Understanding the physiology and pathology of the heart and circulation is the foundation for improving the treatment and prevention of cardiovascular diseases. Wayne State University has an outstanding track record in providing extensive training in the cardiovascular sciences and an exceptional record in the training of minority students in the Detroit metropolitan area, contributing a major role in research education in the region. This new T32 proposal seeks financial support to strengthen our research training effort in the development of a new generation of scientists who will not only pursue cardiovascular research to improve health care, but also strengthen our economic base by innovations that will be translated to medical practice. This proposal encompasses a focused program of excellence in training predoctoral graduate students in cardiovascular research. Based on a selective team of 14 training faculty with complementary scientific expertise in cardiovascular physiology and diseases, the new Detroit Cardiovascular Training Program will emphasize preparing 21st century scientists with strong backgrounds in molecular mechanisms of cardiovascular health and diseases, who are equipped with integrative and translational approaches to scientific investigation. The goal of this new program is to support 4 predoctoral trainees per year. Trainees will be selected from an excellent pool of candidates, including under-represented minorities who may come from an NIH-supported Initiative for Maximizing Student Diversity (IMSD) program. In addition to externally funded active individual research programs with proven training productivity, our training faculty has a long-standing history of joint research an training collaborations. This strong research environment enables us to provide multidisciplinary training in cardiovascular science through a combination of didactic courses and mentored research in areas including hypertension, cardiac muscle contractility, heart failure, myocardial ischemia-reperfusion injury, and cardiovascular adaptation. The training program provides comprehensive didactic and practical instructions in the responsible conduct of research. Career development training will include research seminars and workshops focusing on writing and presentation skills and fellowship and research grant writing and evaluation. Exceptional institutional commitment is in place to support our Program. Operation of the Program will be monitored by a Steering Committee consisting of the Program Director, Program Coordinator, and three training faculty members. The Program will be reviewed regularly by an Internal Advisory Committee in consultation with external advisors. The Department of Physiology Office staff will provide administrative support to the personnel, accounting, and programmatic operations of the Program.