Training in Neurodegenerative Diseases

描述（由申请人提供）：神经变性训练计划（NTP）的目标是在神经变性和涉及神经变性的疾病机制的各个方面提供严格的博士前培训。优秀的学员将与世界一流的教师结合，研究广泛的神经变性相关主题，涵盖蛋白质结构，细胞和分子生物学以及体外和体内疾病模型等研究领域。NTP跨越部门，学校和机构，包括凯斯西储大学的多个部门，特别是医学院及其附属机构，大学医院病例医学中心（UHCMC），路易斯斯托克斯克利夫兰退伍军人管理医疗中心（VAMC）和克利夫兰诊所基金会（CCF，包括勒纳研究所）。所有这些机构彼此都在步行距离之内，这种丰富的培训环境享有非常活跃的基础科学和临床活动以及最先进的资源，以丰富从事神经退行性疾病领域基础和/或转化研究的博士预科学员的培训。国家毒理学规划的培训包括国家毒理学规划课程、正式和非正式研讨会、年度务静会以及学术出版物的研究经历。该培训计划的一个独特组成部分是包括一个学期，每周半天，在神经退行性疾病诊所的指导经验。NTP提供的教学和体验式培训机会的结合将为受训者在神经变性科学探究的未来职业生涯奠定坚实的基础。

DESCRIPTION (provided by applicant): The goal of the Neurodegeneration Training Program (NTP) is to provide rigorous pre-doctoral training in various aspects of neurodegeneration and mechanisms of diseases involving neurodegeneration. An outstanding pool of trainees will combine with world-class faculty to investigate a wide range of neurodegeneration-related topics spanning research areas such as protein structure, cell and molecular biology and in vitro and in vivo models of disease. The NTP spans departments, schools and institutions to include multiple departments at Case Western Reserve University, particularly the School of Medicine, and its affiliated institutions, University Hospitals Case Medical Center (UHCMC), The Louis Stokes Cleveland Veteran's Administration Medical Center (VAMC), and the Cleveland Clinic Foundation (CCF, including the Lerner Research Institute). All of these institutions are within walking distance of each other and this rich training environment enjoys very active basic science and clinical activities and state of the art resources to enrich the training of pre- doctoal trainees as they engage in basic and/or translational research in the field of neurodegeneration. Training in the NTP involves NTP course work, formal and informal seminars, an annual retreat, and a research experience resulting in scholarly publications. A unique component of this training program is the inclusion of a required 1 semester, half day per week, mentored experience in a neurodegenerative disease clinic. The combination of didactic and experiential training opportunities afforded by the NTP will provide trainees a solid foundation for a future career in the scientific inquiry of neurodegeneration.