Chronic Low Back Pain in Older Adults: The Role of Co-Existing Hip Impairments

老年人慢性腰痛：共存髋关节损伤的作用

• 批准号: 9053416
• 负责人: Gregory E Hicks
• 金额: $ 45.97万
• 依托单位: UNIVERSITY OF DELAWARE
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-01 至 2018-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9053416
• 关键词: Address; Age; Aging; Algorithms; Arthralgia; Articular Range of Motion; Characteristics; Chronic low back pain; Clinical; Cohort Studies; Communities; Data; Development; Elderly; Evaluation; Failure; Functional disorder; Future; Goals; Hip Joint; Hip region structure; Impairment; Individual; Intervention; Knowledge; Low Back Pain; Measurement; Musculoskeletal; NIH Program Announcements; Outcome; Pain; Pain management; Patients; Physical Function; Physical therapy; Population; Prevalence; Prevention; Public Health; Rehabilitation therapy; Reporting; Research; Research Personnel; Risk Factors; Role; Series; Severities; Subgroup; Symptoms; Syndrome; Testing; Therapeutic; Vertebral column; Vulnerable Populations; Work; age group; aged; base; chronic pain; cost; design; disability; follow-up; functional decline; functional disability; health care service utilization; improved; personalized care; prevent; prospective; research study; therapeutic evaluation; therapy design

DESCRIPTION (provided by applicant): Low back pain (LBP) is the most frequently reported musculoskeletal problem among older adults. In this age group, LBP has been associated with a host of negative consequences, including increases in mobility limitations, disability and healthcare utilization. Although LBP is a risk factor for functional decline in the elderly, the majority of research studies addressing LBP exclude people over the age of 60; therefore, clinicians have minimal evidence upon which to base their treatment decisions. The long-term goal of this line of work is to develop and test a comprehensive, standardized rehabilitation approach for older adults with chronic LBP that is specifically designed to reduce pain and optimize function. Due to the failure of many one-size-fits-all interventions for LBP, researchers have concluded that patients with LBP do not belong to one homogeneous group, but rather should be classified into subgroups that share similar clinical characteristics to better individualize care and improve clinical outcomes. Our promising preliminary work suggests that one such subgroup in the elderly population with chronic LBP is comprised of individuals with co-existing hip impairments (i.e. hip joint pain, morning stiffness and range of motion limitations). Our data suggest that these hip impairments, which are potentially modifiable through rehabilitation interventions, are more prevalent among older adults with chronic LBP and are associated with greater LBP severity and disability. In the past, others have discussed the concept of hip-spine syndrome, but it has not been systematically studied or adequately addressed from a rehabilitative intervention standpoint. The central hypothesis of this work is that, among older adults, co-existing hip impairments contribute to the development and persistence of chronic LBP, as well as to a greater level of pain-related disability and functional limitations. We propose a prospective cohort study of 250 older adults (aged 60-85 years) with a new or recent onset of LBP. We will perform a series of clinical hip assessments at baseline and follow up for 12 months. The specific aims of this proposal are to investigate whether: (1) the presence and magnitude of clinical hip impairments at baseline predict the development of chronic LBP and greater LBP-related disability among older adults; (2) the presence and magnitude of clinical hip impairments at baseline predict a greater decline in physical function over the course of 12 months among older adults with a recent onset of LBP, and;(3) the presence and magnitude of clinical hip impairments at baseline predict a greater decline in societal participation over the course of 12 months among older adults with a recent onset of LBP. This study will lay the ground work for developing a therapeutic algorithm for evaluation and treatment of LBP, specifically for older adults, to focus on prevention of chronic LBP and development of functional limitations and disability.

描述（由申请人提供）：腰痛（LBP）是老年人中最常见的肌肉骨骼问题。在这个年龄组中，LBP与一系列负面后果有关，包括移动限制，残疾和医疗保健利用的增加。虽然LBP是老年人功能下降的一个危险因素，但大多数针对LBP的研究都排除了60岁以上的人;因此，临床医生只有很少的证据来支持他们的治疗决策。这一系列工作的长期目标是为患有慢性LBP的老年人开发和测试一种全面，标准化的康复方法，该方法专门用于减轻疼痛和优化功能。由于许多一刀切的LBP干预措施的失败，研究人员得出结论，LBP患者不属于一个同质组，而是应该分为具有相似临床特征的亚组，以更好地个性化护理并改善临床结局。我们有希望的初步工作表明，慢性LBP老年人群中的一个这样的亚组由同时存在髋关节损伤（即髋关节疼痛，晨僵和活动范围限制）的个体组成。我们的数据表明，这些髋关节损伤，这是潜在的修改通过康复干预，是更普遍的老年人与慢性LBP，并与更大的LBP严重程度和残疾。在过去，其他人已经讨论了髋关节脊柱综合征的概念，但它还没有被系统地研究或从康复干预的角度充分解决。这项工作的中心假设是，在老年人中，共同存在的髋关节损伤有助于慢性LBP的发展和持续，以及更高水平的疼痛相关残疾和功能障碍。 局限性。我们提出了一个前瞻性队列研究250名老年人（年龄60-85岁）与新的或最近发生的LBP。我们将在基线和随访12个月时进行一系列临床髋关节评估。本提案的具体目的是调查：（1）基线时临床髋关节损伤的存在和程度是否可预测老年人慢性LBP和更严重的LBP相关残疾的发展;（2）基线时临床髋关节损伤的存在和程度是否可预测最近发生LBP的老年人在12个月内身体功能的更大下降;（3）基线时临床髋关节损伤的存在和程度预测最近发作LBP的老年人在12个月的过程中社会参与的下降幅度更大。这项研究将为开发一种用于评估和治疗LBP的治疗算法奠定基础，特别是针对老年人，重点是预防慢性LBP和功能限制和残疾的发展。