Training Program in Translational Biology and Molecular Medicine

转化生物学和分子医学培训项目

• 批准号: 9064776
• 负责人: CLIONA M ROONEY
• 金额: $ 41.5万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2020-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9064776
• 关键词: Biology; Molecular Medicine; Training Programs

 DESCRIPTION (provided by applicant): This application is for continued support of the Translational Biology and Molecular Medicine (TBMM) graduate program at Baylor College of Medicine (BCM). The TBMM program was founded in 2004 based on the strategic plan of the College to establish new interdisciplinary programs that will drive a new model of integration of biomedical research, clinical patient care and education. The first TBMM class matriculated in 2005 and there are currently 62 students in the program and 33 total graduates. The program counts over 200 participating faculty, of which a core group of 127 are current T32-training faculty. The interdisciplinary faculty members have their primary appointments in 7 clinical and 8 basic science departments and offer research opportunities to T32-trainees in a variety of translational biomedical research areas. The major goal of the TBMM program is to train biomedical PhD scientists to work at the interface of basic and clinical research and more effectively exploit the findings of basic and clinical research to improve human health. To achieve this goal, we have during the prior funding period continue to enhance an established (now in its 9th year) unique PhD program with an innovative curriculum and dual mentorship by a basic science mentor and a clinical mentor of research projects that incorporate biomedical sciences with pathophysiology and medical principles. Although still early since inception, our outcomes data begin to show that we have been successful in recruiting and educating students who graduate with a solid education in basic science, pathophysiology and clinical translational research, prepared to become independent investigators performing translational research at the interface between basic and clinical medicine. Students publish their thesis research in high-impact journals in their respective areas and the program is also promoting interdisciplinary translational research through student-driven collaborations between basic and clinical science mentors. Supported by our growing applicant pool and current student body, we are requesting a total of eight funded positions, an increase from our 6 currently funded positions. Motivated by success of this approach in the prior cycle, we request this funding will again support students in their second and third years of graduate school when they are involved in clinical training as well as pursuing their translational research projects. This funding will allow the TBMM program to continue to mature and graduate translational researchers, who are beginning to make a difference in the field of translational research in academic and non-academic careers. It will also allow us to continue to promote and document ways of effective interaction between basic and clinical investigators and to successfully train a new type of PhD graduate to fill the nationa need to lead future translational research efforts.

 描述（由应用程序提供）：此应用是为了持续支持贝勒医学院（BCM）的转化生物学和分子医学（TBMM）研究生课程。 TBMM计划建立在2004年基于该学院的战略计划，该计划建立了新的跨学科计划，该计划将推动生物医学研究，临床患者护理和教育的新模型。第一个TBMM班级于2005年成立，目前该计划中有62名学生和33名毕业生。该计划计算了200多名参与教职员工，其中127人是当前的T32培训教师。跨学科的教职员工在7个临床和8个基础科学部门中有主要任命，并为各种翻译的生物医学研究领域的T32-培训提供了研究机会。 TBMM计划的主要目标是培训生物医学博士学位科学家在基础和临床研究的界面上工作，并更有效地探索基本和临床研究的发现，以改善人类健康。为了实现这一目标，我们在上一期的资金期间继续增强了一项既定的（现在已经是第9年）独特的博士学位计划，并通过基础科学的基础科学和研究项目的临床心理进行了创新的课程和双重心理，该研究项目将生物医学科学与病理生理学和医学原则结合在一起。尽管自成立以来仍然很早，但我们的结果数据开始表明，我们已经成功地招募和教育了那些在基础科学，病理生理学和临床转化研究领域接受良好教育的学生，准备成为基础医学和临床医学之间界面上翻译研究的独立研究人员。学生在各自领域的高影响力期刊上发表论文研究，该计划还通过基本和临床科学指导者之间的学生驱动的合作来促进跨学科的翻译研究。在我们不断增长的适用游泳池和当前学生团体的支持下，我们要求总共八个资助职位，这比我们目前的6个资助职位增加了。在上一周循环中这种方法成功的动机，我们要求这笔资金再次支持学生 他们的第二年和三年研究生院参与临床培训以及进行转化研究项目。这笔资金将使TBMM计划能够继续成熟和研究生翻译研究人员，他们开始在学术和非学术职业的转化研究领域有所作为。它还将使我们能够继续促进和记录基本研究人员和临床研究人员之间有效互动的方法，并成功培训新型的博士学位毕业生，以满足国家需求，以领导未来的转化研究工作。