Adjustment Problems and Substance Use in 3 Generations

第三代的适应问题和物质使用

• 批准号: 9233429
• 负责人: DEBORAH M. CAPALDI
• 金额: $ 10万
• 依托单位: OREGON SOCIAL LEARNING CENTER, INC.
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-06-20 至 2018-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9233429
• 关键词: Accounting; Address; Adolescence; Adult; Age; Age of Onset; Alcohol abuse; Alcohol consumption; Alcohol dependence; Alcohol or Other Drugs use; Alcoholic Beverages; Alcohols; Awareness; Behavior; Biological; Child; Child Rearing; Childhood; Collection; Communities; Couples; Data; Data Analyses; Data Collection; Data Set; Development; Diagnosis; Drug usage; Etiology; Family; Fathers; Feeling suicidal; Generations; Genetic; Growth; Health; Impairment; Individual; Intervention; Longitudinal Studies; Marijuana; Measurement; Measures; Modeling; Mothers; Nicotine; Oregon; Outcome; Outcome Assessment; Parents; Pathway interactions; Pattern; Peer Group; Prevalence; Process; Psychopathology; Public Health; Recording of previous events; Reporting; Risk; Risk Behaviors; Risk Factors; Role; Sample Size; Sampling; Severities; Suicide attempt; System; Testing; Time; Tobacco; Violent injury; Youth; alcohol measurement; antisocial behavior; conduct problem; contextual factors; cost effective; critical developmental period; dating violence; deviant; early adolescence; early childhood; glucuronyl glucosamine glycan sulfate; intergenerational; intimate partner violence; marijuana use; men; peer; peer influence; prospective; retention rate; sex risk; social; suicidal behavior; suicidal risk; time use; transmission process

DESCRIPTION (provided by applicant): Three Generational Study We proposes to study intergenerational transmission of alcohol, tobacco, and other drug use (ATOD) across three generations (G1, G2, and G3). We will use children in the Three Generational Study (3GS), a community sample consisting of up to two of the biological children (G3) of at-risk early adult men (G2) in the Oregon Youth Study (OYS). Multiple indicators of ATOD in G3 will be assessed, including age of onset of use and growth in use over early to midadolescence. A dynamic developmental systems approach focusing on both general pathway psychopathology and outcome-specific risk factors will be used to examine the developmental pathways of precursors (e.g., ATOD awareness) and of the emergence of these behaviors from early childhood to adolescence. Hypotheses regarding cross-generational congruence in the onset and growth of ATOD also will be examined, as well as the transmission of contextual risk and problematic behaviors across three generations, and parenting behaviors and peer influences across two generations. Additionally, the role of ATOD in the etiology of three public health problems; namely health-risking sexual behavior, suicidal thoughts and behaviors, and dating violence will be tested. The OYS men show high levels of antisocial behavior (at age 25 years, 42% had two or more arrests) and substance use (estimated 50% lifetime diagnoses for alcohol dependence or abuse and 50% prevalence of marijuana use in the mid 20s). The men are currently ages 36-38 years and, with their parents (G1), have been involved in the OYS since the G2 men were ages 9-10 years. Specific Aims will be addressed through the collection and analysis of data that will expand the sample size for the early time points (ages 3 to 11 years) and extend the study to ages 19-20 years. Additionally, we will undertake secondary data analysis of the OYS, OYS-Couples Study, and 3GS extant data sets from the beginning of the proposed study period.

描述（由申请人提供）：三代研究我们建议研究跨三代（G1，G2和G3）的酒精，烟草和其他药物使用（ATOD）的代际传递。我们将在三代研究（3GS）中使用儿童，这是一个社区样本，由俄勒冈州青年研究（OYS）中处于风险中的早期成年男性（G2）的两个生物学子女（G3）组成。将评估G3中ATOD的多个指标，包括开始使用的年龄和青少年早期至中期的使用增长。将使用动态发育系统方法来检查前体的发育途径（例如，ATOD意识）以及这些行为从幼儿期到青春期的出现。关于ATOD发病和发展的跨代一致性的假设也将被检查，以及跨三代的背景风险和问题行为的传递，以及跨两代的养育行为和同伴影响。此外，ATOD在三个公共卫生问题的病因学中的作用，即健康风险性行为，自杀想法和行为，以及约会暴力将被测试。OYS男性表现出高水平的反社会行为（在25岁时，42%有两次或两次以上的逮捕）和物质使用（估计50%的终身诊断为酒精依赖或滥用，50%的大麻使用率在20年代中期）。这些男性目前年龄在36-38岁之间，自G2男性9-10岁以来，他们与父母（G1）一起参与了OYS。将通过收集和分析数据来解决特定目的，这将扩大早期时间点（3 - 11岁）的样本量，并将研究扩展至19-20岁。此外，我们将从拟定研究期开始对OYS、OYS夫妇研究和3GS现有数据集进行二次数据分析。