Understanding Alcohol Use Over Time in Early Mid-Adulthood for At-Risk Men

了解高危男性在成年早期的饮酒情况

• 批准号: 7944144
• 负责人: DEBORAH M. CAPALDI
• 金额: $ 66.9万
• 依托单位: OREGON SOCIAL LEARNING CENTER, INC.
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7944144
• 关键词: Abbreviations; Adolescence; Adolescent; Adult; Age; Alcohol abuse; Alcohol consumption; Alcohol dependence; Alcohol or Other Drugs use; Alcohols; Area; Attention; Behavior; Behavioral; Characteristics; Childhood; Chronic; Communities; Comorbidity; Companions; Complex; Crime; DSM-IV; Data; Data Collection; Data Set; Dependence; Development; Developmental Process; Diagnosis; Diagnostic; Diagnostic and Statistical Manual; Disease; Distress; Etiology; Event; Family; Family member; Frequencies; Future; Gambling; Genetic Risk; Growth; Healthy People 2010; Heterogeneity; Hour; Illicit Drugs; Impairment; Individual; Intervention; Intoxication; Lead; Learning; Life; Light; Longevity; Longitudinal Studies; Maintenance; Marijuana; Marijuana Smoking; Measurement; Measures; Mediating; Michigan; Modeling; Non-Prescription Drugs; Normal Range; Occupations; Oregon; Outcome; Parenting behavior; Parents; Pathway interactions; Patient Self-Report; Pattern; Pharmaceutical Preparations; Police; Prevalence; Prevention; Problem behavior; Process; Psychopathology; Recording of previous events; Records; Reporting; Research Personnel; Risk; Risk Behaviors; Risk Factors; Sampling; Severities; Shapes; Societies; Staging; Stress; Substance abuse problem; System; Techniques; Terminology; Testing; Time; Tobacco; Tobacco use; Unemployment; Violence; Youth; aged; alcohol behavior; alcohol consequences; alcohol related problem; alcohol risk; alcohol screening; alcohol use disorder; anti social; base; boys; cohort; contextual factors; data modeling; depressive symptoms; drinking; early adolescence; early alcohol use; economic cost; emerging adult; experience; externalizing behavior; fourth grade; high risk; low socioeconomic status; man; men; mortality; offender; peer; peer influence; prospective; public health relevance; social; treatment effect

DESCRIPTION (provided by applicant): The proposed study would examine issues related to the course, including persistence and desistance, of alcohol use and AUDs in early midadulthood for men. Such behaviors are costly to society both financially and in personal and family distress. These issues would be examined by utilizing an existing longitudinal data set currently spanning later childhood to ages 31-32 years, including 23 yearly assessments of alcohol use, and adding two new waves of data collection at ages 35-36 and 37-38 years. Combining these two new waves with existing data from ages 29-30, 30-31, and 31-32 will provide a total of 5 waves in the early midadult period. The multimethod/multiagent study of a community sample at risk for conduct problem and other risk behaviors began with two cohorts of fourth-grade boys (total N = 206); the retention rate at the last wave was 95% of living subjects (N = 191, ages 31-32 years). The study focused on contextual, family of origin, and peer risk factors based on a social learning model, and data are available on romantic partners. We plan to use a Dynamic Developmental Systems approach, based on aspects of past and current social- contextual influences, to study heterogeneity in the course of alcohol use and AUDs and predictors of the course, including general and specific risk factors within the realms of family, peer, psychopathology, and early to midadult risk and social influences, including romantic partner behaviors. Early onset of alcohol use was assessed prospectively by age at first drink and age at first drunken experience. Association of growth and heterogeneity in growth of alcohol use will be examined also in relation to heterogeneity in the course of co- morbid substance use (tobacco, marijuana, other illicit drugs, non-prescription and over-the-counter drugs), and gambling behavior. In addition, prediction models of treatment seeking will be examined. The two new assessments will include self-report, peer report, and records data (police and DMV records). Reports from intimate partners are available in a companion study. A variety of complementary developmental modeling and prediction techniques will be used to capture the degree to which prior family and contextual factors, and prior behaviors in childhood and adolescence (e.g., antisocial behavior in childhood) and similar contextual, social relationships, and behavioral factors in adulthood, can explain changes in the course of behaviors across the early adult period. PUBLIC HEALTH RELEVANCE: Alcohol use in early mid-adulthood is extremely costly at the personal, family, community, and national levels, and is associated with early mortality. Alcohol abuse/dependence is the most common of all DSM disorders for men. Almost one in four victims of violent crime report that the offender had been drinking prior to the crime. The economic costs of alcohol abuse and dependence were estimated at close to $200 billion in the U.S. in 1998. Focus areas of Healthy People 2010 (U.S. DHHS) include prevention and control of the use of tobacco and substance abuse. The proposed study will shed new light on the persistence and desistance of use of alcohol and other substances in early midadulthood for men from at-risk backgrounds.

描述（由申请人提供）：拟议的研究将研究与男性中年早期饮酒和 AUD 的过程相关的问题，包括持续性和停止性。这种行为给社会带来经济上以及个人和家庭痛苦方面的高昂代价。这些问题将通过利用目前涵盖童年后期至 31-32 岁的现有纵向数据集进行检查，其中包括对酒精使用情况的 23 年度评估，并在 35-36 岁和 37-38 岁增加两波新的数据收集。将这两个新波与 29-30、30-31 和 31-32 岁的现有数据相结合，将提供中成年早期总共 5 个波。对存在行为问题和其他危险行为风险的社区样本进行的多方法/多主体研究始于两组四年级男孩（总数 N = 206）；最后一波的存活受试者的保留率为 95%（N = 191，年龄 31-32 岁）。该研究基于社会学习模型，重点关注背景、原生家庭和同伴风险因素，并且可以获得有关浪漫伴侣的数据。我们计划使用动态发展系统方法，基于过去和当前社会背景影响的各个方面，来研究饮酒过程中的异质性以及AUD和过程的预测因素，包括家庭、同伴、精神病理学领域内的一般和特定风险因素，以及早中期风险和社会影响，包括浪漫伴侣的行为。通过首次饮酒年龄和首次醉酒经历年龄来前瞻性评估早期饮酒情况。酒精使用增长与异质性之间的关联也将与共病物质使用过程中的异质性（烟草、大麻、其他非法药物、非处方药和非处方药）以及赌博行为进行研究。此外，还将检查寻求治疗的预测模型。两项新评估将包括自我报告、同行报告和记录数据（警察和 DMV 记录）。亲密伴侣的报告可在同伴研究中找到。将使用各种互补的发展模型和预测技术来捕获先前的家庭和背景因素以及儿童和青少年时期的先前行为（例如儿童时期的反社会行为）以及成年时期的类似背景、社会关系和行为因素可以解释成年早期行为过程变化的程度。 公共卫生相关性：中青年时期饮酒对个人、家庭、社区和国家层面造成的代价极其高昂，并且与过早死亡有关。酒精滥用/依赖是男性所有 DSM 疾病中最常见的。几乎四分之一的暴力犯罪受害者表示，犯罪者在犯罪前曾饮酒。 1998 年，美国酗酒和酗酒造成的经济损失估计接近 2000 亿美元。2010 年健康人民 (U.S. DHHS) 的重点领域包括预防和控制烟草使用和药物滥用。这项拟议的研究将为来自高危背景的男性在成年早期持续和停止使用酒精和其他物质提供新的线索。