COBRE Center for Evolutionary and Theoretical Immunology

COBRE 进化和理论免疫学中心

• 批准号: 9034588
• 负责人: ERIC SAMUEL LOKER
• 金额: $ 113.25万
• 依托单位: UNIVERSITY OF NEW MEXICO
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-06-01 至 2019-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9034588
• 关键词: Academia; Area; Biology; Businesses; Cellular biology; Centers of Research Excellence; Controlled Environment; Dependence; Economics; Equipment; Extramural Activities; Faculty; Funding; Goals; Grant; Growth; Immunology; Individual; Laboratories; Low income; Mentors; Modeling; Molecular Biology; New Mexico; Paper; Participant; Phase; Pilot Projects; Publishing; Research; Research Infrastructure; Research Personnel; Scientist; Secure; United States National Institutes of Health; base; comparative; computer science; cost; improved; infrastructure development; interest; programs; stem; success; tenure track; waiver

With funding from the NIH IDeA COBRE program, the Center for Evolutionary and Theoretical Immunology (CETI) was launched in 2003. CETI's thematic focus area, in evolutionary-comparative and theoretical immunology, stems from a unique confluence of faculty with shared interests in the Departments of Biology and Computer Science at UNM and at the Los Alamos National Laboratories. With COBRE support, CETI has hired six tenure-track faculty and has leveraged 16,000 SF of new building space in the Biology building to accommodate our program. CETI investigators have now published 576 scientific papers and successfully competed for $39.9 million in research funds. In addition, one of CETI's key goals is to improve and maintain scientific infrastructure to enable our scientists to be even more competitive in securing extramural support. Towards that end, along with our supportive Administrative Core, we have established three extensively-used scientific Cores: a Molecular Biology Core and a Controlled Environments Core, both established in Phase I of our funding, and a Cell Biology Core established in Phase II. Our goals for Phase III are to further improve and expand our three scientific Cores through purchase of additional equipment and hiring of technical support. We also propose to further increase our user base by continuing our popular Pilot Project and Waiver programs. To go along with these programs, we offer all participants extensive mentoring to increase their likelihood of securing their own extramural funding and increasing their prospects for long term success in academia. Another important goal of Phase III is to transition each of our Cores to a cost neutral status, thus reducing our dependence on COBRE support. Consequently, we will phase in business models that will help us achieve this goal by the end of Phase III. Finally, to aid in transition from COBRE support, we have secured a pledge of $887,500 in support from UNM's administration to be applied post-Phase III (in years 16 through 20 of CETI's existence) to help us sustain CETI's independence. By building a critical mass of investigators able to compete for both individual and multi-PI grants, we are confident that CETI will achieve the goals of the IDeA program in promoting increased research competitiveness and scientific infrastructure development in the state of New Mexico.

在 NIH IDeA COBRE 计划的资助下，进化和理论免疫学中心 (CETI) 于 2003 年启动。CETI 的主题重点领域是进化比较和理论 免疫学源于生物系具有共同兴趣的教师的独特融合 新墨西哥大学和洛斯阿拉莫斯国家实验室的计算机科学。在 COBRE 的支持下，CETI 聘请了六名终身教授，并利用了生物大楼 16,000 平方英尺的新建筑空间 以适应我们的计划。 CETI 研究人员现已发表 576 篇科学论文 成功竞争 3990 万美元的研究经费。此外，CETI 的主要目标之一是提高 并维护科学基础设施，使我们的科学家在确保安全方面更具竞争力 校外支持。为此，在我们的支持性行政核心的帮助下，我们建立了 三个广泛使用的科学核心：分子生物学核心和受控环境核心 我们的资金第一阶段建立了，第二阶段建立了细胞生物学核心。我们的阶段目标 III是通过购买额外的设备和技术来进一步改进和扩展我们的三个科学核心 雇用技术支持。我们还建议通过继续受欢迎的方式进一步扩大我们的用户群 试点项目和豁免计划。为了配合这些计划，我们为所有参与者提供广泛的 提供指导，以增加他们获得校外资金并增加前景的可能性 为了在学术界取得长期成功。第三阶段的另一个重要目标是将我们的每个核心转变为 成本中立状态，从而减少我们对 COBRE 支持的依赖。因此，我们将分阶段实施 商业模式将帮助我们在第三阶段结束时实现这一目标。最后，为了帮助从 COBRE 支持，我们已获得新墨西哥大学行政部门承诺提供 887,500 美元的支持 第三阶段后（CETI 存在的第 16 至 20 年）帮助我们维持 CETI 的独立性。经过 建立足够数量的研究人员，能够竞争个人和多 PI 资助，我们正在 相信 CETI 将实现 IDeA 计划在促进加强研究方面的目标 新墨西哥州的竞争力和科学基础设施发展。