COBRE Center for Evolutionary and Theoretical Immunology

在NIH IDEA Cobre计划的资助下，进化和理论免疫学中心 (CETI)于2003年推出。CETI的主题重点领域，进化-比较和理论 免疫学，源于生物系有着共同兴趣的教职员工的独特汇聚 以及在UNM和洛斯阿拉莫斯国家实验室的计算机科学。在Cobre的支持下，CETI 聘请了6名终身教职员工，并利用了生物大楼16,000平方英尺的新建筑空间 来适应我们的节目。CETI调查人员现在已经发表了576篇科学论文和 成功争取到3990万美元的研究资金。此外，CETI的主要目标之一是改进 并维护科学基础设施，使我们的科学家在确保 校外支持。为此，我们与我们的支持性行政核心一起，建立了 三个广泛使用的科学核心：分子生物学核心和受控环境核心，两者都是 在我们的资金第一阶段建立，在第二阶段建立一个细胞生物学核心。我们在第二阶段的目标 三是通过购买更多设备和扩大我们的三个科学核心 聘请技术支持人员。我们还建议通过继续我们广受欢迎的 试点项目和豁免计划。为了配合这些计划，我们为所有参与者提供广泛的 辅导以增加他们获得自己外部资金的可能性，并增加他们的前景 在学术界取得长期成功。第三阶段的另一个重要目标是将我们的每个核心过渡到 成本中立的地位，从而减少我们对Cobre支持的依赖。因此，我们将分阶段实施 将帮助我们在第三阶段结束时实现这一目标的商业模式。最后，帮助我们从 Cobre支持，我们已经从UNM管理部门获得了88.75万美元的支持承诺，以供申请 第三阶段后(在CETI存在的第16年到第20年)，以帮助我们维持CETI的独立性。通过 建立一支足够多的调查人员，能够竞争个人和多项PI拨款，我们正在 相信CETI将在促进更多研究方面实现IDEA计划的目标 新墨西哥州的竞争力和科学基础设施发展。

With funding from the NIH IDeA COBRE program, the Center for Evolutionary and Theoretical Immunology (CETI) was launched in 2003. CETI's thematic focus area, in evolutionary-comparative and theoretical immunology, stems from a unique confluence of faculty with shared interests in the Departments of Biology and Computer Science at UNM and at the Los Alamos National Laboratories. With COBRE support, CETI has hired six tenure-track faculty and has leveraged 16,000 SF of new building space in the Biology building to accommodate our program. CETI investigators have now published 576 scientific papers and successfully competed for $39.9 million in research funds. In addition, one of CETI's key goals is to improve and maintain scientific infrastructure to enable our scientists to be even more competitive in securing extramural support. Towards that end, along with our supportive Administrative Core, we have established three extensively-used scientific Cores: a Molecular Biology Core and a Controlled Environments Core, both established in Phase I of our funding, and a Cell Biology Core established in Phase II. Our goals for Phase III are to further improve and expand our three scientific Cores through purchase of additional equipment and hiring of technical support. We also propose to further increase our user base by continuing our popular Pilot Project and Waiver programs. To go along with these programs, we offer all participants extensive mentoring to increase their likelihood of securing their own extramural funding and increasing their prospects for long term success in academia. Another important goal of Phase III is to transition each of our Cores to a cost neutral status, thus reducing our dependence on COBRE support. Consequently, we will phase in business models that will help us achieve this goal by the end of Phase III. Finally, to aid in transition from COBRE support, we have secured a pledge of $887,500 in support from UNM's administration to be applied post-Phase III (in years 16 through 20 of CETI's existence) to help us sustain CETI's independence. By building a critical mass of investigators able to compete for both individual and multi-PI grants, we are confident that CETI will achieve the goals of the IDeA program in promoting increased research competitiveness and scientific infrastructure development in the state of New Mexico.