COBRE Center for Evolutionary and Theoretical Immunology

在NIH IDEA COBRE项目的资助下，进化与理论免疫学中心（Center for Evolutionary and Theoretical Immunology） （CETI）于2003年启动。CETI的专题重点领域，在演变-比较和理论 免疫学，源于一个独特的融合教师在生物学系的共同利益 在新墨西哥大学和洛斯阿拉莫斯国家实验室学习计算机科学。在COBRE的支持下，CETI 聘请了六名终身教职员工，并在生物大楼利用了16，000平方英尺的新建筑空间 来配合我们的计划CETI的研究人员已经发表了576篇科学论文， 成功争取到3990万美元的研究经费。此外，CETI的主要目标之一是提高 并维护科学基础设施，使我们的科学家在确保安全方面更具竞争力 校外支持为此，我们沿着我们的支持性行政核心， 三个广泛使用的科学核心：分子生物学核心和受控环境核心， 在我们的资金的第一阶段建立，并在第二阶段建立细胞生物学核心。我们的阶段目标 三是通过购买额外的设备，进一步改善和扩大我们的三个科学核心， 聘请技术支持。我们亦建议继续推行广受欢迎的 试点项目和豁免计划。为了沿着这些计划，我们为所有参与者提供广泛的 指导，以增加他们获得自己的校外资金的可能性，并增加他们的前景 在学术界取得长期成功。第三阶段的另一个重要目标是将我们的每个核心转换为 成本中立地位，从而减少我们对COBRE支持的依赖。因此，我们将分阶段 这些商业模式将帮助我们在第三阶段结束时实现这一目标。最后，为了帮助从 COBRE的支持，我们已经从UNM的行政部门获得了887，500美元的支持承诺， 第三阶段后（CETI成立后的16年至20年），以帮助我们维持CETI的独立性。通过 建立一个临界质量的研究人员能够竞争个人和多PI赠款，我们是 相信CETI将实现IDEA计划在促进研究增长方面的目标 竞争力和科学基础设施的发展在新墨西哥州。

With funding from the NIH IDeA COBRE program, the Center for Evolutionary and Theoretical Immunology (CETI) was launched in 2003. CETI's thematic focus area, in evolutionary-comparative and theoretical immunology, stems from a unique confluence of faculty with shared interests in the Departments of Biology and Computer Science at UNM and at the Los Alamos National Laboratories. With COBRE support, CETI has hired six tenure-track faculty and has leveraged 16,000 SF of new building space in the Biology building to accommodate our program. CETI investigators have now published 576 scientific papers and successfully competed for $39.9 million in research funds. In addition, one of CETI's key goals is to improve and maintain scientific infrastructure to enable our scientists to be even more competitive in securing extramural support. Towards that end, along with our supportive Administrative Core, we have established three extensively-used scientific Cores: a Molecular Biology Core and a Controlled Environments Core, both established in Phase I of our funding, and a Cell Biology Core established in Phase II. Our goals for Phase III are to further improve and expand our three scientific Cores through purchase of additional equipment and hiring of technical support. We also propose to further increase our user base by continuing our popular Pilot Project and Waiver programs. To go along with these programs, we offer all participants extensive mentoring to increase their likelihood of securing their own extramural funding and increasing their prospects for long term success in academia. Another important goal of Phase III is to transition each of our Cores to a cost neutral status, thus reducing our dependence on COBRE support. Consequently, we will phase in business models that will help us achieve this goal by the end of Phase III. Finally, to aid in transition from COBRE support, we have secured a pledge of $887,500 in support from UNM's administration to be applied post-Phase III (in years 16 through 20 of CETI's existence) to help us sustain CETI's independence. By building a critical mass of investigators able to compete for both individual and multi-PI grants, we are confident that CETI will achieve the goals of the IDeA program in promoting increased research competitiveness and scientific infrastructure development in the state of New Mexico.