Predoctoral Interdepartmental Training Program in Neuroscience

神经科学博士前跨部门培训计划

• 批准号: 8870450
• 负责人: KRISTEN A KEEFE
• 金额: $ 21.84万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-01 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8870450
• 关键词: Neurosciences; Training Programs; pre-doctoral

DESCRIPTION (provided by applicant): Research in the neurosciences has become increasingly interdisciplinary: it is not possible to understand the nervous system by focusing on a narrow area of expertise. The principle underlying the graduate education offered by the University of Utah Interdepartmental Neuroscience Program is that students approach a problem from a very broad perspective. The approach includes the application of a diversity of techniques that range across molecular biology, electrophysiology, classical embryology and behavioral protocols. The diverse techniques are unified by two intellectual approaches that have made the University of Utah famous: the study of human disease and a tradition of excellence in the field of genetics. Fifty one NIH- funded training faculty members, chosen from among 76 neuroscientists in 13 departments at the University of Utah, are aligned in five specific areas of research in neuroscience: Molecular Neurobiology, Cellular Neuroscience, Development, Brain and Behavior, and Neurobiology. These five areas reflect the breadth of the program and provide exceptional opportunities to the 45 current students. This renewal application requests funding for three first year and three second year Ph.D. students in the Interdepartmental Program in Neuroscience. All of the training positions in the previous award period were filled and funding for the same number of trainees is requested in the present application. Due to the outstanding neuroscience training program, recent graduates have been placed in excellent postdoctoral fellowships at Yale, Stanford, Harvard, U Mass, UCSD, and UCSF. There is no doubt that trainees from the Interdepartmental Neuroscience Program will continue to become future leaders in neuroscience research.

描述（由申请人提供）：神经科学的研究已经变得越来越多的跨学科：它是不可能通过专注于一个狭窄的专业领域来了解神经系统。犹他州大学跨部门神经科学项目所提供的研究生教育的基本原则是，学生从一个非常广泛的角度来处理一个问题。该方法包括应用分子生物学、电生理学、经典胚胎学和行为学协议等多种技术。不同的技术是由两个智力方法，使犹他州著名的统一：人类疾病的研究和遗传学领域的卓越传统。从犹他州大学13个系的76名神经科学家中选出的51名NIH资助的培训教员在神经科学的五个特定研究领域保持一致：分子神经生物学，细胞神经科学，发育，大脑和行为，以及神经生物学。这五个领域反映了该计划的广度，并为目前的45名学生提供了特殊的机会。这个更新申请要求资助三个第一年和三个第二年博士学位。学生在神经科学跨部门计划。上一个奖学金期的所有培训职位都已填补，本申请要求为同样数量的受训人员提供资金。由于出色的神经科学培训计划，最近的毕业生已被安排在耶鲁大学，斯坦福大学，哈佛，马萨诸塞大学，加州大学圣地亚哥分校和加州大学旧金山分校优秀的博士后奖学金。毫无疑问，跨部门神经科学计划的学员将继续成为神经科学研究的未来领导者。

项目成果

Imaging activity in astrocytes and neurons with genetically encoded calcium indicators following in utero electroporation.

• DOI: 10.3389/fnmol.2015.00010
• 发表时间: 2015
• 期刊: Frontiers in molecular neuroscience
• 影响因子: 4.8
• 作者: Gee JM;Gibbons MB;Taheri M;Palumbos S;Morris SC;Smeal RM;Flynn KF;Economo MN;Cizek CG;Capecchi MR;Tvrdik P;Wilcox KS;White JA
• 通讯作者: White JA

Antiseizure drugs differentially modulate θ-burst induced long-term potentiation in C57BL/6 mice.

• DOI: 10.1111/epi.12524
• 发表时间: 2014-02
• 期刊: Epilepsia
• 影响因子: 5.6
• 作者: West PJ;Saunders GW;Remigio GJ;Wilcox KS;White HS
• 通讯作者: White HS

Repeated low-dose kainate administration in C57BL/6J mice produces temporal lobe epilepsy pathology but infrequent spontaneous seizures.

对 C57BL/6J 小鼠重复低剂量红藻氨酸给药会产生颞叶癫痫病理，但很少发生自发性癫痫发作。

• DOI: 10.1016/j.expneurol.2016.02.014
• 发表时间: 2016
• 期刊: Experimental neurology
• 影响因子: 5.3
• 作者: Umpierre,AnthonyD;Bennett,IsaiahV;Nebeker,LismoreD;Newell,ThomasG;Tian,BruceB;Thomson,KyleE;White,HSteve;White,JohnA;Wilcox,KarenS
• 通讯作者: Wilcox,KarenS

Impaired flexibility in decision making in rats after administration of the pharmacological stressor yohimbine.

• DOI: 10.1007/s00213-014-3529-y
• 发表时间: 2014-10
• 期刊: PSYCHOPHARMACOLOGY
• 影响因子: 3.4
• 作者: Schwager, Andrea L.;Haack, Andrew K.;Taha, Sharif A.
• 通讯作者: Taha, Sharif A.