Pattern Recognition Receptors in Inflammation and Infection

先天免疫是我们抵御感染的第一道防线，但病原体可以克服这一系统。了解微生物如何破坏先天免疫可以教我们如何预防和/或治疗传染病。先天免疫通过引发炎症起作用。当这一过程失调时，许多重要的急性和慢性疾病就会发生。因此，阻断先天免疫有可能治疗许多疾病。该项目旨在了解这些背景下的先天免疫。

Innate immunity provides our first line of defence against infections, but pathogens can overcome this system. Understanding how microbes disable innate immunity can teach us how to prevent and/or treat infectious diseases. Innate immunity acts by initiating inflammation. Many important acute and chronic diseases develop when this process is dysregulated. Blocking innate immunity thus has potential to treat many diseases. This project aims to understand innate immunity in these contexts.