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Phenotypic and functional characterisation of CD4 T helper 22 cells and their role in the regulation of chronic allergic disease of the lung and skin

Phenotypic and functional characterisation of CD4 T helper 22 cells and their role in the regulation of chronic allergic disease of the lung and skin
CD4 T辅助细胞22的表型和功能特征及其在肺和皮肤慢性过敏性疾病调节中的作用
批准号:
nhmrc : 1061413
负责人:
Prof Paul Foster
金额:
$47.61万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2017-12-31

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中文摘要
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英文摘要
Allergic inflammatory diseases such as asthma and allergic dermatitis are major health problems in our community that lead to poor quality of life. These diseases are induced by activation of immune cells known as T helper (Th) lymphocytes. Recently Th22 cells have been identified in patients with allergic diseases. In this study we will, for the first time, characterise these cells and determine their role in the processes that lead to chronic inflammation in asthma and allergic dermatitis.
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