Alterations in secretion and gene expression in pancreatic beta cells exposed to lipid.

暴露于脂质的胰腺β细胞的分泌和基因表达发生变化。

• 批准号: nhmrc : 230850
• 负责人: Prof Trevor Biden
• 金额: $ 28.36万
• 依托单位: Garvan Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2003
• 资助国家: 澳大利亚
• 起止时间: 2003-01-01 至 2005-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/alterations-secretion-gene-exposed-lipid/96704
• 关键词: Alterations; secretion; gene; expression; pancreatic

The project is aimed at a better understanding of the way in which fats control gene expression in the pancreatic beta cells of the islets of Langerhans. Because changes in gene expression are to likely to explain why exposure of these cells to fat disrupts their ability to release insulin, identification of these genes could explain why only some obese people develop Type 2 diabetes.

该项目旨在更好地了解脂肪控制胰岛β细胞基因表达的方式。因为基因表达的变化可能解释为什么这些细胞暴露于脂肪会破坏它们释放胰岛素的能力，所以这些基因的鉴定可以解释为什么只有一些肥胖的人会患上2型糖尿病。