The knotty problem of enterochromaffin cells and gastro-intestinal function: Unravelling cause and effect

肠嗜铬细胞与胃肠功能的棘手问题：揭开因果关系

• 批准号: nhmrc : 510202
• 负责人: A/Pr Lu Liu
• 金额: $ 26.88万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/knotty-problem-enterochromaffin-cause-effect/100715
• 关键词: knotty; problem; enterochromaffin; cells; gastro

It is crucial to understand how the food we eat controls the secretions and movements of a healthy or a diseased gastrointestinal (GI) system. One way control is achieved involves the release of serotonin (5-HT) from the enterochromaffin cells present in the epithelial lining of the intestine. This is the subject of our proposal and our results will help us to understand the causes of GI disorders and help to formulate new treatments.

了解我们吃的食物如何控制健康或患病胃肠道（GI）系统的分泌和运动至关重要。其中一种控制方法是从肠上皮细胞释放5-羟色胺（5-HT）。这是我们建议的主题，我们的结果将有助于我们了解胃肠道疾病的原因，并有助于制定新的治疗方法。