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The Mechanisms of Epithelial Cell Survival that Govern Thymus Function

The Mechanisms of Epithelial Cell Survival that Govern Thymus Function
控制胸腺功能的上皮细胞存活机制
批准号:
nhmrc : 1121325
负责人:
A/Pr Daniel Gray
金额:
$42.39万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 2019-12-31

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中文摘要
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英文摘要
The thymus is an organ dedicated to the production of crucial immune cells, called T lymphocytes. Cancer treatments, such as radiation or chemotherapy, destroy thymic function and impair immune recovery in patients. We aim to uncover molecular processes that govern the life and death decisions of cells in the thymus. Our goal is to then use this information to develop treatments to protect this critical organ from damage and improve immune recovery following radiation or chemotherapy.
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Targeting Cell Death Pathways in Immune Pathology and Cancer
  • 批准号:
    nhmrc : GNT1158024
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $64.92万
  • 财政年份:
    2019
  • 负责人:
    A/Pr Daniel Gray
  • 依托单位:
Targeting Caspase 8 in T-Cell Homeostasis and Disease
  • 批准号:
    nhmrc : GNT1145888
  • 项目类别:
    Project Grants
  • 资助金额:
    $121.58万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Daniel Gray
  • 依托单位:
Targeting Caspase 8 in T-Cell Homeostasis and Disease
The Mechanisms of Epithelial Cell Survival that Govern Thymus Function
  • 批准号:
    nhmrc : GNT1121325
  • 项目类别:
    Project Grants
  • 资助金额:
    $62.1万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Daniel Gray
  • 依托单位:
海外基金