Antigen presentation in health and disease

健康和疾病中的抗原呈递

• 批准号: nhmrc : GNT1154502
• 负责人: Prof Jose Villadangos
• 金额: $ 78.54万
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/antigen-presentation-health-disease/1349141
• 关键词: Antigen; presentation; health; disease

The research program I will carry out during this fellowship will characterise how the immune system detects and starts responses against pathogens and cancer cells. I will describe proteins and intracellular processes required to fulfil this function, which may be harnessed to develop more effective vaccines against infections, protect critically ill patients from hospital acquired infections, prevent autoimmunity and fight cancer.

我将在这个奖学金期间进行的研究计划将揭示免疫系统如何检测并启动对病原体和癌细胞的反应。我将描述实现这一功能所需的蛋白质和细胞内过程，这些蛋白质和细胞内过程可能被用来开发更有效的抗感染疫苗，保护重症患者免受医院获得性感染，预防自身免疫和对抗癌症。