Gas chromatograph with electron capture detector for analysis of fluorinated organic compounds

带电子捕获检测器的气相色谱仪，用于分析氟化有机化合物

• 批准号: 344937-2007
• 负责人: VanHamme, Jonathan
• 金额: $ 5.53万
• 依托单位: Thompson Rivers University
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2006
• 资助国家: 加拿大
• 起止时间: 2006-01-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=326038
• 关键词: Gas; chromatograph; electron; capture; detector

The environmental persistence, toxicity and distribution of halogenated organic chemicals is an increasingly troubling issue. After historical experience with chlorinated chemicals such as DDT and PCBs, the chemical industry turned to fluorinated and brominated compounds to manufacture products such as non-stick coatings and water proofing chemicals (perfluorinated chemicals; PFCs), and flame retardants (polybrominated diphenyl ethers; PBDEs). Many of these compounds, once deemed safe, are now being banned as their toxic effects are discovered and their presence in animals as far away as the Arctic is realized. Other compounds, such as haloacetic acids (HAAs) and trihalomethanes (THMs) are dangerous byproducts that may be formed during drinking water disinfection with chlorine. This work aims to strengthen our understanding of the distribution and fate of these chemicals and to explore microbiological methods to render them non-toxic. In addition, another chlorinated compound of historical significance, the chemical warfare agent Mustard Gas, is a primary target of this research. Canada recently announced the discovery of an undisclosed quantity of this dangerous material 127 km off the coast of Vancouver Island, and the United States possesses 7 tonnes of this material that is awaiting destruction.

卤化有机化学品的环境持久性、毒性和分布是一个日益令人不安的问题。在经历了 DDT 和 PCB 等氯化化学品的历史经验之后，化学工业转向使用氟化和溴化化合物来生产不粘涂料和防水化学品（全氟化学品；PFC）和阻燃剂（多溴二苯醚；PBDE）等产品。许多曾经被认为是安全的化合物现在已被禁止，因为它们的毒性作用被发现，而且远至北极的动物体内也存在它们。其他化合物，如卤乙酸 (HAAs) 和三卤甲烷 (THM) 是危险的副产品，可能在用氯消毒饮用水时形成。这项工作旨在加强我们对这些化学物质的分布和归宿的理解，并探索微生物方法使其无毒。此外，另一种具有历史意义的氯化化合物，化学战剂芥子气，是这项研究的主要目标。加拿大最近宣布在距温哥华岛海岸 127 公里处发现了这种危险物质，数量未公开，美国拥有 7 吨这种物质等待销毁。