Regulation of toxin production in Clostridium difficile
Regulation of toxin production in Clostridium difficile
批准号:
nhmrc : 545836
负责人:
Prof Dena Lyras
金额:
$31.48万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2011-12-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The research aims to determine how toxin production is controlled in an emerging bacterial pathogen that is a major cause of gastrointestinal infections in hospitals. We will determine the nature of the external signals and the mechanisms by which the bacterium uses those signals to regulate toxin production. These studies will significantly expand our knowledge of how this important bacterium causes disease, a key to developing new methods for the control and treatment of disease.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Understanding how bacteria adapt and function in the complex gut ecosystem
-
批准号:FL210100258
-
项目类别:Australian Laureate Fellowships
-
资助金额:$224.17万
-
财政年份:2022
-
负责人:Prof Dena Lyras
-
依托单位:
Mechanism of secretion of large clostridial toxins
-
批准号:DP210103374
-
项目类别:Discovery Projects
-
资助金额:$44.51万
-
财政年份:2021
-
负责人:Prof Dena Lyras
-
依托单位:
A link between antibiotic resistance and bacterial sporulation
-
批准号:DP190102969
-
项目类别:Discovery Projects
-
资助金额:$30.95万
-
财政年份:2019
-
负责人:Prof Dena Lyras
-
依托单位:
Mechanism of action of a novel multifunctional bacterial secretion system
-
批准号:DP180102449
-
项目类别:Discovery Projects
-
资助金额:$28.88万
-
财政年份:2018
-
负责人:Prof Dena Lyras
-
依托单位:
From Lead Compounds to Potential Therapeutics: Drugs to Treat Clostridium Difficile Infections
-
批准号:nhmrc : 1124032
-
项目类别:Project Grants
-
资助金额:$35.72万
-
财政年份:2017
-
负责人:Prof Dena Lyras
-
依托单位:
Global regulatory networks that control virulence in Clostridium perfringens
-
批准号:nhmrc : 1125349
-
项目类别:Project Grants
-
资助金额:$36.28万
-
财政年份:2017
-
负责人:Prof Dena Lyras
-
依托单位:
Global regulatory networks that control virulence in Clostridium perfringens
-
批准号:nhmrc : GNT1125349
-
项目类别:Project Grants
-
资助金额:$53.16万
-
财政年份:2017
-
负责人:Prof Dena Lyras
-
依托单位:
From Lead Compounds to Potential Therapeutics: Drugs to Treat Clostridium Difficile Infections
-
批准号:nhmrc : GNT1124032
-
项目类别:Project Grants
-
资助金额:$52.35万
-
财政年份:2017
-
负责人:Prof Dena Lyras
-
依托单位:
The role of Clostridium difficile spore interactions with the host in gastrointestinal infection and disease
-
批准号:nhmrc : 1107969
-
项目类别:Project Grants
-
资助金额:$35.07万
-
财政年份:2016
-
负责人:Prof Dena Lyras
-
依托单位:
The role of Clostridium difficile spore interactions with the host in gastrointestinal infection and disease
-
批准号:nhmrc : GNT1107969
-
项目类别:Project Grants
-
资助金额:$51.15万
-
财政年份:2016
-
负责人:Prof Dena Lyras
-
依托单位:
Environmental contamination and pig disease: an Australian microbe evolves
-
批准号:DP150104670
-
项目类别:Discovery Projects
-
资助金额:$28.66万
-
财政年份:2015
-
负责人:Prof Dena Lyras
-
依托单位:
The Development Of Novel Antibacterials Targeting Clostridium Difficile Infections
-
批准号:nhmrc : 1051105
-
项目类别:Project Grants
-
资助金额:$50.05万
-
财政年份:2013
-
负责人:Prof Dena Lyras
-
依托单位:
Molecular characterisation of hypervirulence and the infectious cycle in Clostridium difficile
-
批准号:FT120100779
-
项目类别:ARC Future Fellowships
-
资助金额:$60.58万
-
财政年份:2012
-
负责人:Prof Dena Lyras
-
依托单位:
The development and evaluation of a new therapy for the prevention and treatment of bacterial infections in hospitals
-
批准号:LP110200752
-
项目类别:Linkage Projects
-
资助金额:$35.45万
-
财政年份:2011
-
负责人:Prof Dena Lyras
-
依托单位:
The role of virulence factors of Clostridium difficile in food animals.
-
批准号:DP1093891
-
项目类别:Discovery Projects
-
资助金额:$22.99万
-
财政年份:2010
-
负责人:Prof Dena Lyras
-
依托单位:
Functional biology of large serine recombinases from mobile antibiotic resistance elements
-
批准号:nhmrc : 436639
-
项目类别:NHMRC Project Grants
-
资助金额:$29.09万
-
财政年份:2007
-
负责人:Prof Dena Lyras
-
依托单位:
Pathogenesis of clostridial myonecrosis
-
批准号:nhmrc : 236859
-
项目类别:NHMRC Project Grants
-
资助金额:$9.12万
-
财政年份:2003
-
负责人:Prof Dena Lyras
-
依托单位:
Functional biology of clostridial transposons
-
批准号:nhmrc : 194228
-
项目类别:NHMRC Project Grants
-
资助金额:$17.41万
-
财政年份:2002
-
负责人:Prof Dena Lyras
-
依托单位:
国内基金
海外基金
登录
查看更多内容
金葡菌α-toxin 通过NMDAR-TNFR1-necrosome调控成骨细胞程序性
坏死的研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2024
-
负责人:初翔
-
依托单位:
马唐生防菌活性成分ES-toxin生物合成关键基因鉴定及功能研究
-
批准号:31901902
-
项目类别:青年科学基金项目
-
资助金额:24.0万元
-
批准年份:2019
-
负责人:张晶旭
-
依托单位:
肺炎支原体CARDS Toxin基因缺失对其毒力影响的研究
-
批准号:81401678
-
项目类别:青年科学基金项目
-
资助金额:23.0万元
-
批准年份:2014
-
负责人:薛冠华
-
依托单位:
自噬通路在艰难梭菌毒素杀伤宿主细胞过程中的作用探究
-
批准号:31170126
-
项目类别:面上项目
-
资助金额:55.0万元
-
批准年份:2011
-
负责人:魏文胜
-
依托单位:
紫茎泽兰致病型链格孢菌毒素(AAC-toxin)在病原体侵染寄主过程中的产生和作用
-
批准号:31000834
-
项目类别:青年科学基金项目
-
资助金额:20.0万元
-
批准年份:2010
-
负责人:陈世国
-
依托单位:
植物激素在番茄对链格孢菌和AAL-toxin抗性中的作用机制
-
批准号:30970244
-
项目类别:面上项目
-
资助金额:29.0万元
-
批准年份:2009
-
负责人:汪俏梅
-
依托单位:
大肠杆菌O157:H7基因组中未知功能O岛的研究
-
批准号:30371279
-
项目类别:面上项目
-
资助金额:18.0万元
-
批准年份:2003
-
负责人:任志鸿
-
依托单位: