Global regulatory networks that control virulence in Clostridium perfringens

控制产气荚膜梭菌毒力的全球监管网络

• 批准号: nhmrc : GNT1125349
• 负责人: Prof Dena Lyras
• 金额: $ 53.16万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/global-regulatory-networks-clostridium-perfringens/1347473
• 关键词: Global; regulatory; networks; control; virulence

This research focuses on the bacterium that is responsible for clostridial myonecrosis, or gas gangrene, an often fatal human infection. The objective is to determine how this bacterium controls the production of the various factors that are required to cause disease. The aims will be achieved by the integrated application of the latest techniques in microbiology and molecular biology and will result in a significant advancement in our knowledge of this complex regulatory process.

这项研究的重点是细菌，是负责梭菌肌坏死，或气性坏疽，往往致命的人类感染。目的是确定这种细菌如何控制引起疾病所需的各种因子的产生。这些目标将通过微生物学和分子生物学最新技术的综合应用来实现，并将使我们对这一复杂的调控过程的了解取得重大进展。