Research Fellowship

研究奖学金

• 批准号: nhmrc : 1022469
• 负责人: A/Pr Jorg Heierhorst
• 金额: $ 45.06万
• 依托单位: St. Vincent's Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/research-fellowship/110192
• 关键词: Research; Fellowship

DNA damage response pathways play important roles in preventing the onset of cancer and regulating the clinical response to chemotherapeutics, and some of the relevant proteins have additional functions during normal development. This fellowship will study new a human protein with key roles in the formation of the lung, and its roles in preventing devastating consequences of normal oxidative damage to DNA, as well as additional fundamental mechanisms involved in preventing genome mutations.

DNA损伤反应途径在预防癌症的发生和调节对化疗药物的临床反应中起着重要作用，并且一些相关蛋白在正常发育过程中具有额外的功能。该奖学金将研究一种新的人类蛋白质，该蛋白质在肺的形成中具有关键作用，其在预防正常氧化损伤对DNA的破坏性后果中的作用，以及参与预防基因组突变的其他基本机制。