Developmental functions of a novel Zinc-finger protein

新型锌指蛋白的发育功能

• 批准号: nhmrc : 1009763
• 负责人: A/Pr Jorg Heierhorst
• 金额: $ 44.46万
• 依托单位: St. Vincent's Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/developmental-functions-novel-finger-protein/109424
• 关键词: Developmental; functions; novel; Zinc; finger

Diseases of the respiratory track and the immune system represent major public health burdens, from the common cold and lung cancer, to increased risk of infections and auto-immune diseases. We have identified a new gene that is essential for lung development, and required for normal development of antibody-producing immune cells. Here we want to define the mechanism by which this gene functions, in order to better understand how lungs and immune cells develop.

呼吸道和免疫系统疾病是主要的公共卫生负担，从普通感冒和肺癌到感染和自身免疫性疾病的风险增加。我们发现了一种新基因，它对于肺部发育至关重要，并且是产生抗体的免疫细胞正常发育所必需的。在这里，我们想要定义该基因发挥作用的机制，以便更好地了解肺部和免疫细胞如何发育。