Research Fellowship

研究奖学金

• 批准号: nhmrc : 1044628
• 负责人: Prof Boris Martinac
• 金额: $ 50.13万
• 依托单位: Victor Chang Cardiac Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/research-fellowship/111676
• 关键词: Research; Fellowship

Ion channels are molecular pores of excitable membranes facilitating passage of ions and organic solutes across cellular membranes. An ever-increasing number of human and animal diseases result from malfunctioning ion channels making them to important therapeutic targets, which are modulated by a range of currently prescribed drugs. In the recent years the scientific and medical community has become increasingly aware of the role that mechanosensitive ion channels play in pathology of diseases including cardiac hyperthrophy and arrhythmias.

离子通道是可激膜上的分子孔，促进离子和有机溶质通过细胞膜。越来越多的人类和动物疾病是由于离子通道故障导致它们到达重要的治疗靶点，而这些靶点是由一系列目前的处方药调节的。近年来，科学界和医学界越来越意识到机械敏感离子通道在包括心脏肥厚和心律失常在内的疾病病理中的作用。