Mechanosensory Biophysics Program

机械感觉生物物理学计划

• 批准号: nhmrc : GNT1135974
• 负责人: Prof Boris Martinac
• 金额: $ 77.45万
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/mechanosensory-biophysics-program/1348018
• 关键词: Mechanosensory; Biophysics; Program

Mechanotransduction is defined as the ability of living cells to respond to and convert mechanical stimuli into electro-chemical cellular signals to ensure survival. It is largely dependent on membrane proteins known as mechanosensitive (MS) ion channels. These channels are involved in senses of hearing and touch, and are also crucial regulators of heart and muscle function. This research aims to elucidate the general physical principles underlying mechanotransduction in living cells.

机械转导被定义为活细胞响应机械刺激并将其转化为电化学细胞信号以确保生存的能力。它很大程度上依赖于称为机械敏感 (MS) 离子通道的膜蛋白。这些通道涉及听觉和触觉，也是心脏和肌肉功能的重要调节器。这项研究旨在阐明活细胞中机械转导的一般物理原理。