Mechanosensory Biophysics Program

机械转导被定义为活细胞对机械刺激作出反应并将其转化为电化学细胞信号以确保生存的能力。它很大程度上依赖于被称为机械敏感（MS）离子通道的膜蛋白。这些通道与听觉和触觉有关，也是心脏和肌肉功能的关键调节器。本研究旨在阐明活细胞机械转导的一般物理原理。

Mechanotransduction is defined as the ability of living cells to respond to and convert mechanical stimuli into electro-chemical cellular signals to ensure survival. It is largely dependent on membrane proteins known as mechanosensitive (MS) ion channels. These channels are involved in senses of hearing and touch, and are also crucial regulators of heart and muscle function. This research aims to elucidate the general physical principles underlying mechanotransduction in living cells.