Engineering of a novel export system for industrially important amino acids

工业重要氨基酸的新型输出系统的工程

• 批准号: DP180102813
• 负责人: Prof Boris Martinac
• 金额: $ 26.81万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-07-01 至 2021-11-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP180102813
• 关键词: Engineering; novel; export; system; industrially

This project aims to understand the gating mechanism of MscCG (a major amino acid exporter) and improve the amino acid production by designing a highly effective MscCG-like export system for selective membrane transport of industrially relevant amino acids. Amino acid production is one of the most promising global markets, driven by growing meat consumption in developing countries. The project aims to elucidate the three-dimensional structure of MscCG and identify important parts. In doing so, the project aims to design more efficient and economic amino acid production.

该项目旨在了解MscCG（主要氨基酸输出体）的门控机制，并通过设计一种高效的类似MscCG的输出系统来选择性膜运输工业相关氨基酸来提高氨基酸产量。在发展中国家肉类消费不断增长的推动下，氨基酸生产是最有前途的全球市场之一。该项目旨在阐明 MscCG 的三维结构并确定重要部分。在此过程中，该项目旨在设计更高效、更经济的氨基酸生产。