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RNA-DIRECTED EPIGENETIC REMODELLING IN CANCER

RNA-DIRECTED EPIGENETIC REMODELLING IN CANCER
RNA 引导的癌症表观遗传重塑
批准号:
nhmrc : 1010620
负责人:
Prof Susan Clark
金额:
$47.93万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2013-12-31

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中文摘要
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英文摘要
Epigenetics describes how genes can be turned off or on without changing the DNA sequence. Epigenetics plays a major role in cancer development. In this proposal we are investigating a novel hypothesis that in cancer a similar mechanism to imprinting USING NON-CODING RNA is triggered and this promotes the suppression of clusters of genes. The results from this proposal will have major implications to our understanding of gene regulation in cancer and will have important therapeutic value for cancer treatment.
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会议论文
Unravelling The Cancer Epigenome: Mechanisms to Translation
  • 批准号:
    nhmrc : GNT1156408
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $88.83万
  • 财政年份:
    2019
  • 负责人:
    Prof Susan Clark
  • 依托单位:
Epigenomics of Human Disease
  • 批准号:
    nhmrc : GNT1063559
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $82.29万
  • 财政年份:
    2014
  • 负责人:
    Prof Susan Clark
  • 依托单位:
Determining the causes and consequences of epigenetic remodelling in cancer and disease
  • 批准号:
    nhmrc : 1063559
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $57.57万
  • 财政年份:
    2014
  • 负责人:
    Prof Susan Clark
  • 依托单位:
Modelling epigenomic change during early breast carcinogenesis using in vitro and in vivo model systems
  • 批准号:
    nhmrc : 1029579
  • 项目类别:
    Project Grants
  • 资助金额:
    $49.57万
  • 财政年份:
    2012
  • 负责人:
    Prof Susan Clark
  • 依托单位:
国内基金
海外基金
晶态桥联聚倍半硅氧烷的自导向组装(self-directed assembly)及其发光性能
  • 批准号:
    21171046
  • 项目类别:
    面上项目
  • 资助金额:
    55.0万元
  • 批准年份:
    2011
  • 负责人:
    李焕荣
  • 依托单位: