Determining the causes and consequences of epigenetic remodelling in cancer and disease

确定癌症和疾病表观遗传重塑的原因和后果

• 批准号: nhmrc : 1063559
• 负责人: Prof Susan Clark
• 金额: $ 57.57万
• 依托单位: Garvan Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/determining-causes-consequences-cancer-disease/455065
• 关键词: Determining; causes; consequences; epigenetic; remodelling

The study of epigenetics and its role in gene control is proving to be the next major contributor to our future understanding and improvement of health outcomes. Professor Clark and her team are on a quest to unravel the secrets of human epigenome to help reduce the burden of human disease. Their research will help contribute to the discovery of genetic and epigenetic aberrations in cancer and other complex diseases with the development of new diagnostic tests and potential new epigenetic-based therapies.

表观遗传学及其在基因控制中的作用的研究被证明是我们未来理解和改善健康结果的下一个主要贡献者。克拉克教授和她的团队正在探索揭开人类表观基因组的秘密，以帮助减轻人类疾病的负担。他们的研究将有助于发现癌症和其他复杂疾病的遗传和表观遗传畸变，并开发新的诊断测试和潜在的基于表观遗传的新疗法。