The role of amyloid beta in insulin resistance

β淀粉样蛋白在胰岛素抵抗中的作用

• 批准号: nhmrc : 1027226
• 负责人: A/Pr Sean Mcgee
• 金额: $ 27.69万
• 依托单位: Deakin University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-amyloid-beta-insulin-resistance/110550
• 关键词: role; amyloid; beta; insulin; resistance

The amyloid beta (Ab) protein is implicated in Alzheimer’s Disease through its ability to impair brain metabolism. We have recently found that Ab can also impair metabolism in other tissues. This project will determine the role of Ab in regulating whole body metabolism and determine whether it is implicated in the development of metabolic diseases such as type 2 diabetes.

淀粉样β（Ab）蛋白通过其损害脑代谢的能力而与阿尔茨海默病有关。我们最近发现，抗体也可以损害其他组织的代谢。该项目将确定Ab在调节全身代谢中的作用，并确定它是否与2型糖尿病等代谢疾病的发展有关。