The Role of the Complement System in Neurodegeneration and the Therapeutic Potential of Complement Inhibition

补体系统在神经退行性变中的作用和补体抑制的治疗潜力

• 批准号: nhmrc : 519700
• 负责人: A/Pr Trent Woodruff
• 金额: $ 25.38万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-complement-neurodegeneration-complement-inhibition/115745
• 关键词: Role; Complement; System; Neurodegeneration; Therapeutic

This project aims to identify the role of immune and inflammatory components in the pathology of neurodegenerative disease. Additionally, this research will determine whether a new class of novel anti-inflammatory drugs can alter the neurodegenerative process. This will allow for an increased understanding of the biology of neurodegenerative disease, and also may lead to the development of new treatments for conditions such as Parkinson’s disease, Huntington’s disease and motor neuron disease.

该项目旨在确定免疫和炎症成分在神经退行性疾病病理学中的作用。此外，这项研究将确定一类新的新型抗炎药物是否可以改变神经退行性过程。这将使人们对神经退行性疾病的生物学有更多的了解，也可能导致开发新的治疗方法，如帕金森病，亨廷顿病和运动神经元疾病。